Articles with "tryptase antibody" as a keyword



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An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma

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Published in 2019 at "Cell"

DOI: 10.1016/j.cell.2019.09.009

Abstract: Severe asthma patients with low type 2 inflammation derive less clinical benefit from therapies targeting type 2 cytokines and represent an unmet need. We show that mast cell tryptase is elevated in severe asthma patients… read more here.

Keywords: severe asthma; tryptase; tryptase antibody; anti tryptase ... See more keywords