Palmatine ameliorated murine colitis by suppressing tryptophan metabolism and regulating gut microbiota
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacological Research"
DOI: 10.1016/j.phrs.2018.09.010
Abstract: &NA; Inflammatory bowel disease (IBD), majorly include Crohn's disease (CD) and ulcerative colitis (UC), is chronic and relapsing inflammatory disorders of the gastrointestinal tract, which treatment options remain limited. Here we examined the therapeutic effects… read more here.
Keywords: ameliorated murine; colitis; palmatine ameliorated; gut microbiota ... See more keywords
Systemic tryptophan homeostasis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.897929
Abstract: Tryptophan is an essential amino acid, which is not only a building block for protein synthesis, but also a precursor for the biosynthesis of co-enzymes and neuromodulators, such as NAD/NADP(H), kynurenic acid, melatonin and serotonin.… read more here.
Keywords: tryptophan homeostasis; tdo; systemic tryptophan; tryptophan catabolism ... See more keywords