High interindividual variability of indoxyl sulfate production identified by an oral tryptophan challenge test
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DOI: 10.1038/s41522-025-00651-8
Abstract: Indoxyl sulfate (IS) has been implicated in the pathogenesis of cardiovascular diseases. IS is converted from indole, a metabolite of dietary tryptophan through the action of gut microbial tryptophanase, by two hepatic enzymes: CYP2E1 and… read more here.
Keywords: oral tryptophan; tryptophan challenge; tryptophan; indoxyl sulfate ... See more keywords