UVB Radiation and Selected Tryptophan-Derived AhR Ligands—Potential Biological Interactions in Melanoma Cells
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DOI: 10.3390/ijms22147500
Abstract: Excessive UV exposure is considered the major environmental factor in melanoma progression. Human skin is constantly exposed to selected tryptophan-derived aryl hydrocarbon receptor (AhR) ligands, including kynurenine (KYN) and kynurenic acid (KYNA), as they are… read more here.
Keywords: ahr ligands; tryptophan; melanoma cells; selected tryptophan ... See more keywords
What If Not All Metabolites from the Uremic Toxin Generating Pathways Are Toxic? A Hypothesis
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DOI: 10.3390/toxins14030221
Abstract: The topic of uremic toxicity has received broad attention from the nephrological community over the past few decades. An aspect that is much less often considered is the possibility that the metabolic pathways that generate… read more here.
Keywords: metabolites uremic; toxin; tryptophan derived; derived metabolites ... See more keywords