Chromatographic analysis of tryptophan metabolites
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Separation Science"
DOI: 10.1002/jssc.201700184
Abstract: The kynurenine pathway generates multiple tryptophan metabolites called collectively kynurenines and leads to formation of the enzyme cofactor nicotinamide adenine dinucleotide. The first step in this pathway is tryptophan degradation, initiated by the rate‐limiting enzymes… read more here.
Keywords: analysis tryptophan; chromatographic analysis; tryptophan metabolites; tryptophan ... See more keywords
Shenling Baizhu San ameliorates ulcerative colitis by regulating the gut microbiota and its tryptophan metabolites: A complementary medicine to mesalamine.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2022.115145
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Shenling Baizhu San (SBS) is commonly employed to improve gastrointestinal dysfunction in patients with ulcerative colitis (UC) in China. SBS combined with mesalamine has been demonstrated to result in improve its curative effects… read more here.
Keywords: shenling baizhu; tryptophan metabolites; mesalamine; medicine ... See more keywords
Application of the optimized and validated LC-MS method for simultaneous quantification of tryptophan metabolites in culture medium from cancer cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.112805
Abstract: Kynurenine pathway is the main route of tryptophan degradation generating a number of immunoregulatory compounds. Some conditions like oxidative stress, inflammatory factors might enhance tryptophan degradation. Process is active in several cells including fibroblasts, cancer… read more here.
Keywords: tryptophan metabolites; tryptophan; simultaneous quantification; cancer ... See more keywords
Enhanced Intestinal Barriers by Puerarin in Combination with Tryptophan.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c05830
Abstract: The intestinal barrier is essential for maintaining human intestinal health. The growing number of studies has shown that both puerarin and tryptophan and its metabolites have a beneficial effect on the intestinal barrier. This study… read more here.
Keywords: puerarin tryptophan; combination; tryptophan; tryptophan metabolites ... See more keywords
Lactiplantibacillus plantarum Regulates Intestinal Physiology and Enteric Neurons in IBS through Microbial Tryptophan Metabolites.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c03087
Abstract: Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder characterized by visceral pain and gut dysmotility. However, the specific mechanisms by which Lactobacillus strains relieve IBS remain unclear. Here, we screened Lactobacillus strains from… read more here.
Keywords: tryptophan metabolites; physiology enteric; enteric neurons; physiology ... See more keywords
The Tryptophan Pathway Targeting Antioxidant Capacity in the Placenta
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/1054797
Abstract: The placenta plays a vital role in fetal development during pregnancy. Dysfunction of the placenta can be caused by oxidative stress and can lead to abnormal fetal development. Preventing oxidative stress of the placenta is… read more here.
Keywords: tryptophan pathway; antioxidant capacity; tryptophan metabolites; antioxidant properties ... See more keywords
Platelet Ido1 expression is induced during Plasmodium yoelii infection, altering plasma tryptophan metabolites
Sign Up to like & getrecommendations! Published in 2024 at "Blood Advances"
DOI: 10.1182/bloodadvances.2024013175
Abstract: Key Points • Platelet Ido1 is upregulated in response to IFN-γ including in Plasmodium infection.• Platelets modulate plasma tryptophan metabolites altering kynurenine-to-tryptophan ratios. read more here.
Keywords: tryptophan metabolites; ido1 expression; infection; plasma tryptophan ... See more keywords
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-018-1366-3
Abstract: BackgroundThe host response to intruders in the central nervous system (CNS) may be beneficial but could also be harmful and responsible for neurologic symptoms and sequelae in CNS infections. This immune response induces the activation… read more here.
Keywords: tryptophan metabolites; nervous system; central nervous; neurotoxic tryptophan ... See more keywords
Lactiplantibacillus plantarum attenuate gossypol-induced hepatic lipotoxicity by altering intestinal microbiota for enriching microbial tryptophan metabolites in Nile tilapia (Oreochromis niloticus)
Sign Up to like & getrecommendations! Published in 2025 at "Microbiome"
DOI: 10.1186/s40168-025-02172-0
Abstract: Free fatty acids (FFAs) are the main cause of fatty liver disease, which can be alleviated by modulation of intestinal microbiota. Lactiplantibacillus plantarum plays a key role in maintaining liver health, but the underlying mechanism… read more here.
Keywords: plantarum; tryptophan metabolites; microbial tryptophan; lipotoxicity ... See more keywords
Lung-Gut Microbiota and Tryptophan Metabolites Changes in Neonatal Acute Respiratory Distress Syndrome
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s459496
Abstract: Purpose Neonatal Acute Respiratory Distress Syndrome (NARDS) is a severe respiratory crisis threatening neonatal life. We aim to identify changes in the lung-gut microbiota and lung-plasma tryptophan metabolites in NARDS neonates to provide a differentiated… read more here.
Keywords: tryptophan metabolites; nards neonates; gut microbiota; tryptophan ... See more keywords
Metabonomics reveals that entomopathogenic nematodes mediate tryptophan metabolites that kill host insects
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1042145
Abstract: The entomopathogenic nematode (EPN) Steinernema feltiae, which carries the symbiotic bacterium Xenorhabdus bovienii in its gut, is an important biocontrol agent. This EPN could produce a suite of complex metabolites and toxin proteins and lead… read more here.
Keywords: kill host; insects; host insects; metabonomics reveals ... See more keywords