Fermentative Indole Production via Bacterial Tryptophan Synthase Alpha Subunit and Plant Indole-3-Glycerol Phosphate Lyase Enzymes
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DOI: 10.1021/acs.jafc.2c01042
Abstract: Indole is produced in nature by diverse organisms and exhibits a characteristic odor described as animal, fecal, and floral. In addition, it contributes to the flavor in foods, and it is applied in the fragrance… read more here.
Keywords: tryptophan synthase; indole glycerol; indole production; indole ... See more keywords
Clinical Persistence of Chlamydia trachomatis Sexually Transmitted Strains Involves Novel Mutations in the Functional αββα Tetramer of the Tryptophan Synthase Operon
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DOI: 10.1128/mbio.01464-19
Abstract: Chlamydia trachomatis (Ct) is the most common sexually transmitted bacterium with more than 131 million cases occurring annually worldwide. Ct infections are often asymptomatic, persisting for many years despite treatment. In vitro recovery from persistence… read more here.
Keywords: persistence; sexually transmitted; tryptophan synthase; chlamydia trachomatis ... See more keywords
Light-Regulation of Tryptophan Synthase by Combining Protein Design and Enzymology
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DOI: 10.3390/ijms20205106
Abstract: The spatiotemporal control of enzymes by light is of growing importance for industrial biocatalysis. Within this context, the photo-control of allosteric interactions in enzyme complexes, common to practically all metabolic pathways, is particularly relevant. A… read more here.
Keywords: enzymology; protein design; tryptophan synthase; trpa trpb ... See more keywords
Comparative Coexpression Analysis of Indole Synthase and Tryptophan Synthase A Reveals the Independent Production of Auxin via the Cytosolic Free Indole
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DOI: 10.3390/plants12081687
Abstract: Indole synthase (INS), a homologous cytosolic enzyme of the plastidal tryptophan synthase A (TSA), has been reported as the first enzyme in the tryptophan-independent pathway of auxin synthesis. This suggestion was challenged as INS or… read more here.
Keywords: tryptophan synthase; coexpression; synthase; pathway ... See more keywords