TSC gene expression in the newly diagnosed Egyptian acute leukemia patients
Sign Up to like & getrecommendations! Published in 2018 at "Comparative Clinical Pathology"
DOI: 10.1007/s00580-018-2722-5
Abstract: TSC (tuberous sclerosis) complex is the major negative regulator of mTOR which activates cell cycle progression leading to uncontrolled growth. Acute leukemias are very heterogeneous as a group of hematological malignancies; they arise as a… read more here.
Keywords: tsc gene; gene expression; acute leukemia; leukemia patients ... See more keywords
Analysis of renal lesions in Chinese tuberous sclerosis complex patients with different types of TSC gene mutations
Sign Up to like & getrecommendations! Published in 2022 at "Genetics and Molecular Biology"
DOI: 10.1590/1678-4685-gmb-2020-0387
Abstract: Abstract We sought to explore the relationship between renal lesion features and genetic mutations in tuberous sclerosis complex (TSC) patients. TSC patients with renal lesions were subjected to TSC1/2 gene next-generation sequencing (NGS). TSC1/2 mutation… read more here.
Keywords: tsc gene; renal lesions; patients different; gene ... See more keywords
Tsc Gene Locus Disruption and Differences in Renal Epithelial Extracellular Vesicles
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.630933
Abstract: In tuberous sclerosis complex (TSC), Tsc2 mutations are associated with more severe disease manifestations than Tsc1 mutations and the role of extracellular vesicles (EVs) in this context is not yet studied. We report a comparative… read more here.
Keywords: extracellular vesicles; locus disruption; gene locus; tsc gene ... See more keywords