LAUSR

TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling

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0 Published in 2020 at "Molecular Autism"

DOI: 10.1186/s13229-019-0311-3

Abstract: BackgroundTuberous sclerosis complex (TSC) is a neurodevelopmental disorder with frequent occurrence of epilepsy, autism spectrum disorder (ASD), intellectual disability (ID), and tumors in multiple organs. The aberrant activation of mTORC1 in TSC has led to… read more here.

Keywords: mnk; het; eif4e; het null ... See more keywords