Bafilomycin A1 increases the sensitivity of tongue squamous cell carcinoma cells to cisplatin by inhibiting the lysosomal uptake of platinum ions but not autophagy.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.03.003
Abstract: The role of autophagy in tongue squamous cell carcinoma (TSCC) cisplatin resistance is unclear. We aimed to identify a possible synergistic effect of autophagy inhibitors and cisplatin in TSCC cells and explore the underlying mechanism.… read more here.
Keywords: tongue squamous; platinum; bafilomycin; tscc ... See more keywords
AICAR-induced activation of AMPK inhibits the migration of TSCC cells by targeting ZO-1.
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DOI: 10.1111/odi.13212
Abstract: OBJECTIVE To investigate the effect of AMPK on tight junction (TJ) components, ZO-1 and F-actin, and the underlying mechanisms of AMPK in inhibiting migration of tongue squamous cell carcinoma (TSCC) cells. METHODS Expression and distribution… read more here.
Keywords: migration; activation ampk; activation; tscc cells ... See more keywords