Presynaptic Dysfunction in Neurons Derived from Tay–Sachs iPSCs
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DOI: 10.1016/j.neuroscience.2019.06.026
Abstract: Tay-Sachs disease (TSD) is a GM2 gangliosidosis lysosomal storage disease caused by a loss of lysosomal hexosaminidase-A (HEXA) activity and characterized by progressive neurodegeneration due to the massive accumulation of GM2 ganglioside in the brain.… read more here.
Keywords: neurons derived; tay sachs; ipscs; tsd ipscs ... See more keywords