Articles with "tsg" as a keyword



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Oil-in-water emulsion containing tamarind seed gum during in vitro gastrointestinal digestion: rheological properties, stability, and lipid digestibility.

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Published in 2020 at "Journal of the science of food and agriculture"

DOI: 10.1002/jsfa.10268

Abstract: BACKGROUD Polysaccharides may enhance/inhibit lipid digestibility of oil-in-water (O/W) emulsions because of their emulsifying and/or stabilizing ability and could also affect the formation, stability, and viscosity of emulsions. Tamarind seed gum (TSG) was used as… read more here.

Keywords: seed; tsg; stability; emulsion ... See more keywords

Tumor necrosis factor alpha-stimulated gene-6 (TSG-6) inhibits the inflammatory response by inhibiting the activation of P38 and JNK signaling pathway and decreases the restenosis of vein grafts in rats

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Published in 2017 at "Heart and Vessels"

DOI: 10.1007/s00380-017-1059-3

Abstract: This study aims to explore the effects of tumor necrosis factor alpha-stimulated gene-6 (TSG-6) on vascular inflammatory response and vascular injury in grafted vein wall of rats and its possible mechanism. Vascular grafting model was… read more here.

Keywords: p38 jnk; jnk; tsg; inflammatory response ... See more keywords

TNF-Stimulated Gene-6, Part of Extracellular Vesicles in Adipose Tissue-Derived Mesenchymal Stem Cell Concentrated Conditioned Medium, Affects Microglial Activity

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Published in 2025 at "Journal of Neuroimmune Pharmacology"

DOI: 10.1007/s11481-025-10216-3

Abstract: Identifying the specific bioactive molecules produced by mesenchymal stem cells (MSCs) and the signaling pathways and cell types upon which they act is critical to developing MSC-based therapeutics for inflammatory diseases with high unmet needs.… read more here.

Keywords: tnf stimulated; tsg; stimulated gene; mesenchymal stem ... See more keywords

La protéine TSG-6 induite par l’inflammation contribue au maintien de l’hyaluronan dans l’épiderme humain

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Published in 2020 at "Annales De Dermatologie Et De Venereologie"

DOI: 10.1016/j.annder.2020.08.012

Abstract: TSG-6 est une proteine anti-inflammatoire impliquee dans le remodelage de la matrice extracellulaire. Cette proteine lie l’hyaluronan (HA), le principal glycosaminoglycan present dans les espaces intercellulaires des keratinocytes epidermiques. Dans les epidermes humains reconstruits (RHE) en… read more here.

Keywords: proteine; maintien; tsg; hyaluronan ... See more keywords

TSG-6 - a double-edged sword for osteoarthritis (OA).

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Published in 2018 at "Osteoarthritis and cartilage"

DOI: 10.1016/j.joca.2017.10.019

Abstract: PURPOSE To explore mechanisms underlying the association of TSG-6 with osteoarthritis (OA) progression. METHODS TSG-6-mediated heavy chain (HC) transfer (TSG-6 activity) and its association with inflammatory mediators were quantified in knee OA (n=25) synovial fluids… read more here.

Keywords: tsg activity; osteoarthritis; tsg; tsg double ... See more keywords

Tetrahydroxystilbene glucoside-induced relaxation of the superior mesenteric artery via both endothelium-dependent and endothelium-independent mechanisms.

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Published in 2019 at "Microvascular research"

DOI: 10.1016/j.mvr.2018.10.007

Abstract: Tetrahydroxystilbene glucoside (TSG) is the main water-soluble component in Polygonum multiflorum Thunb, and it has many cardioprotective effects. Although TSG is able to relax blood vessels, its relaxation of rat superior mesenteric arteries and the… read more here.

Keywords: superior mesenteric; endothelium; relaxation; tsg ... See more keywords

Kynurenic acid, an IDO metabolite, controls TSG-6-mediated immunosuppression of human mesenchymal stem cells

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Published in 2017 at "Cell Death and Differentiation"

DOI: 10.1038/s41418-017-0006-2

Abstract: Mesenchymal stem cells (MSCs) have been demonstrated to be anti-inflammatory against various immune disorders through several factors, including indoleamine 2,3-dioxygenase (IDO) and TNF-stimulated gene 6 (TSG-6). However, little is known about the necessity for both… read more here.

Keywords: kynurenic acid; ido; controls tsg; tsg ... See more keywords
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P0145MESENCHYMAL STEM CELLS PROTECT RENAL TUBULAR CELLS VIA TSG-6 REGULATED MACROPHAGE FUNCTION AND PHENOTYPE SWITCHING

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Published in 2020 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfaa142.p0145

Abstract: Tumor necrosis factor-α-induced gene/protein (TSG)-6 is a key factor influencing mesenchymal stem cells (MSCs) immunomodulatory properties, but its renoprotective efficacy is unknown. Using a novel swine model of renal artery stenosis (RAS) complicated by metabolic… read more here.

Keywords: phenotype; tsg; renal tubular; macrophage ... See more keywords

Renal protective effects of extracellular vesicle-encapsulated tumor necrosis factor-α-induced protein 6 derived from mesenchymal stem cells.

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Published in 2025 at "Stem cells"

DOI: 10.1093/stmcls/sxaf022

Abstract: Acute kidney injury (AKI) is involved in subsequent chronic kidney disease (CKD) development, and effective treatments to prevent AKI to CKD progression are lacking. Mesenchymal stem cells (MSCs) are emerging as a promising cellular therapy… read more here.

Keywords: mesenchymal stem; stem cells; mscs; tumor necrosis ... See more keywords

TSG‐6 inhibits hypertrophic scar fibroblast proliferation by regulating IRE1α/TRAF2/NF‐κB signalling

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Published in 2022 at "International Wound Journal"

DOI: 10.1111/iwj.13950

Abstract: TNF‐stimulated gene (TSG‐6) was reported to suppress hypertrophic scar (HS) formation in a rabbit ear model, and the overexpression of TSG‐6 in human HS fibroblasts (HSFs) was found to induce their apoptotic death. The molecular… read more here.

Keywords: traf2 signalling; hypertrophic scar; tsg; proliferation ... See more keywords

TSG Targeting KDM5A Affects Osteogenic Differentiation of Bone Mesenchymal Stem Cells Induced by Bone Morphogenetic Protein 2

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Published in 2022 at "Journal of Healthcare Engineering"

DOI: 10.1155/2022/6472864

Abstract: Objectives To investigate the effect of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) on the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and its molecular mechanism. Methods After TSG treatment of rBMSCs, alkaline phosphatase (ALP) activity was compared… read more here.

Keywords: bone; osteogenic differentiation; tsg; mesenchymal stem ... See more keywords