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   Articles with "tslp" as a keyword



TSLP and TSLPr Expression and Localization in the Airways of COPD and Non‐COPD Patients

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recommendations! Published in 2025 at "European Journal of Immunology"

DOI: 10.1002/eji.202451480

Abstract: Thymic stromal lymphopoietin (TSLP) is an alarmin cytokine activated by allergens, pathogens, and air pollutants. Recent studies suggest TSLP dysregulation in chronic inflammatory diseases. It was highlighted as a key player in the context of… read more here.

Keywords: copd patients; non copd; copd; copd non ... See more keywords

Thymic stromal lymphopoietin is expressed in human corneal stromal cells and secreted upon protease‐activated receptor 1 activation

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recommendations! Published in 2017 at "IUBMB Life"

DOI: 10.1002/iub.1644

Abstract: Thymic stromal lymphopoietin (TSLP) is an interleukin‐7 (IL‐7) like cytokine that triggers inflammatory responses through activating dendritic cell. It is demonstrated to be involved in a number of disorders, including cancer, gastrointestinal diseases, and autoimmune… read more here.

Keywords: corneal; protease; thymic stromal; stromal cells ... See more keywords

TSLP and TSLP receptors variants are associated with smoking

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recommendations! Published in 2019 at "Molecular Genetics & Genomic Medicine"

DOI: 10.1002/mgg3.842

Abstract: To search for new prevention markers for early detection of the diseases caused by tobacco, we aimed to investigate the polymorphisms in TSLP and TSLPRs associated with cigarette smoking in the Saudi population. read more here.

Keywords: tslp receptors; receptors variants; tslp tslp; tslp ... See more keywords

Tumor-derived high-mobility group box 1 and thymic stromal lymphopoietin are involved in modulating dendritic cells to activate T regulatory cells in a mouse model

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recommendations! Published in 2017 at "Cancer Immunology, Immunotherapy"

DOI: 10.1007/s00262-017-2087-7

Abstract: High-mobility group box 1 (HMGB1) is involved in the tumor-associated activation of regulatory T cells (Treg), but the mechanisms remain unknown. In a mouse tumor model, silencing HMGB1 in tumor cells or inhibiting tumor-derived HMGB1… read more here.

Keywords: derived hmgb1; high mobility; tumor derived; tslp ... See more keywords

Relevance of Thymic Stromal Lymphopoietin on the Pathogenesis of Glioblastoma: Role of the Neutrophil

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recommendations! Published in 2024 at "Cellular and Molecular Neurobiology"

DOI: 10.1007/s10571-024-01462-9

Abstract: Glioblastoma multiforme (GBM) is the most predominant and malignant primary brain tumor in adults. Thymic stromal lymphopoietin (TSLP), a cytokine primarily generated by activated epithelial cells, has recently garnered attention in cancer research. This study… read more here.

Keywords: gbm cells; thymic stromal; glioblastoma; gbm ... See more keywords

Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP

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recommendations! Published in 2020 at "Inflammation"

DOI: 10.1007/s10753-020-01367-x

Abstract: Fungal keratitis (FK) is a keratopathy caused by pathogenic fungal infection. The aim of this work is to explore the role of thymic stromal lymphopoietin (TSLP) in FK. Human corneal epithelial cells (HCECs) were treated… read more here.

Keywords: aspergillus fumigatus; tslp; treatment; thp macrophages ... See more keywords
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Sputum IL-25, IL-33 and TSLP, IL-23 and IL-36 in airway obstructive diseases. Reduced levels of IL-36 in eosinophilic phenotype.

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recommendations! Published in 2021 at "Cytokine"

DOI: 10.1016/j.cyto.2021.155421

Abstract: INTRODUCTION Alarmins ((IL-25, IL-33 and thymic stromal lymphopoietin (TSLP)) are known to promote Th2 inflammation and could be associated with eosinophilic airway infiltration. They may also play a role in airway remodeling in chronic airway… read more here.

Keywords: eosinophilic airway; airway obstructive; inflammation; obstructive diseases ... See more keywords

TSLP‐activated dendritic cells induce T helper type 2 inflammation in Aspergillus fumigatus keratitis

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recommendations! Published in 2018 at "Experimental Eye Research"

DOI: 10.1016/j.exer.2018.03.014

Abstract: Abstract Thymic stromal lymphopoietin (TSLP) is an IL‐7‐like cytokine, which is secreted by epithelial cells under the stimulation of Toll‐like receptor (TLR) ligands. Dendritic cells (DCs) which express the thymic stromal lymphopoietin receptor (TSLPR) can… read more here.

Keywords: aspergillus fumigatus; fumigatus keratitis; inflammation; keratitis tslp ... See more keywords

Greasy hair against obesity

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recommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"

DOI: 10.1038/s41392-021-00850-7

Abstract: In their article, Choa et al. open the perspective to loose fat by increasing sebogenesis. Envisioning a T cell-dependent mechanism, they suggest that stimulation of sebum production by thymic stromal lymphopeietin (TSLP) “pulls” lipids out… read more here.

Keywords: regulation; tslp; adipose tissue; sebum production ... See more keywords

Disrupting TSLP–TSLP receptor interactions via putative small molecule inhibitors yields a novel and efficient treatment option for atopic diseases

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recommendations! Published in 2024 at "EMBO Molecular Medicine"

DOI: 10.1038/s44321-024-00085-3

Abstract: Thymic stromal lymphopoietin (TSLP) is a key player in atopic diseases, which has sparked great interest in therapeutically targeting TSLP. Yet, no small-molecule TSLP inhibitors exist due to the challenges of disrupting the protein–protein interaction… read more here.

Keywords: tslp receptor; tslp; small molecule; atopic diseases ... See more keywords

PM2.5 Stimulates Macrophage-Derived Thymic Stromal Lymphopoietin (TSLP) to Induce a Mouse Model of Allergic Conjunctivitis

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recommendations! Published in 2025 at "Current Eye Research"

DOI: 10.1080/02713683.2025.2487066

Abstract: Abstract Purpose Increasing epidemiologic evidence has indicated that PM2.5 exposure is strongly correlated with the prevalence of allergic conjunctivitis (AC), but there is no experimental model for elucidating the underlying mechanism involved. We established a… read more here.

Keywords: pm2; mouse model; pm2 exposure; allergic conjunctivitis ... See more keywords