Thymic stromal lymphopoietin is expressed in human corneal stromal cells and secreted upon protease‐activated receptor 1 activation
Sign Up to like & getrecommendations! Published in 2017 at "IUBMB Life"
DOI: 10.1002/iub.1644
Abstract: Thymic stromal lymphopoietin (TSLP) is an interleukin‐7 (IL‐7) like cytokine that triggers inflammatory responses through activating dendritic cell. It is demonstrated to be involved in a number of disorders, including cancer, gastrointestinal diseases, and autoimmune… read more here.
Keywords: corneal; protease; thymic stromal; stromal cells ... See more keywords
TSLP and TSLP receptors variants are associated with smoking
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.842
Abstract: To search for new prevention markers for early detection of the diseases caused by tobacco, we aimed to investigate the polymorphisms in TSLP and TSLPRs associated with cigarette smoking in the Saudi population. read more here.
Keywords: tslp receptors; receptors variants; tslp tslp; tslp ... See more keywords
Tumor-derived high-mobility group box 1 and thymic stromal lymphopoietin are involved in modulating dendritic cells to activate T regulatory cells in a mouse model
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-017-2087-7
Abstract: High-mobility group box 1 (HMGB1) is involved in the tumor-associated activation of regulatory T cells (Treg), but the mechanisms remain unknown. In a mouse tumor model, silencing HMGB1 in tumor cells or inhibiting tumor-derived HMGB1… read more here.
Keywords: derived hmgb1; high mobility; tumor derived; tslp ... See more keywords
Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation"
DOI: 10.1007/s10753-020-01367-x
Abstract: Fungal keratitis (FK) is a keratopathy caused by pathogenic fungal infection. The aim of this work is to explore the role of thymic stromal lymphopoietin (TSLP) in FK. Human corneal epithelial cells (HCECs) were treated… read more here.
Keywords: aspergillus fumigatus; tslp; treatment; thp macrophages ... See more keywords
Sputum IL-25, IL-33 and TSLP, IL-23 and IL-36 in airway obstructive diseases. Reduced levels of IL-36 in eosinophilic phenotype.
Sign Up to like & getrecommendations! Published in 2021 at "Cytokine"
DOI: 10.1016/j.cyto.2021.155421
Abstract: INTRODUCTION Alarmins ((IL-25, IL-33 and thymic stromal lymphopoietin (TSLP)) are known to promote Th2 inflammation and could be associated with eosinophilic airway infiltration. They may also play a role in airway remodeling in chronic airway… read more here.
Keywords: eosinophilic airway; airway obstructive; inflammation; obstructive diseases ... See more keywords
TSLP‐activated dendritic cells induce T helper type 2 inflammation in Aspergillus fumigatus keratitis
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Eye Research"
DOI: 10.1016/j.exer.2018.03.014
Abstract: Abstract Thymic stromal lymphopoietin (TSLP) is an IL‐7‐like cytokine, which is secreted by epithelial cells under the stimulation of Toll‐like receptor (TLR) ligands. Dendritic cells (DCs) which express the thymic stromal lymphopoietin receptor (TSLPR) can… read more here.
Keywords: aspergillus fumigatus; fumigatus keratitis; inflammation; keratitis tslp ... See more keywords
Greasy hair against obesity
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-021-00850-7
Abstract: In their article, Choa et al. open the perspective to loose fat by increasing sebogenesis. Envisioning a T cell-dependent mechanism, they suggest that stimulation of sebum production by thymic stromal lymphopeietin (TSLP) “pulls” lipids out… read more here.
Keywords: regulation; tslp; adipose tissue; sebum production ... See more keywords
Thymic Stromal Lymphopoietin-Related Allergic Pathway in Patients With Vernal Keratoconjunctivitis
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DOI: 10.1097/ico.0000000000001832
Abstract: Purpose: To investigate the expression of thymic stromal lymphopoietin (TSLP) and the relevant signaling pathways in the giant papillae obtained from patients with vernal keratoconjunctivitis (VKC) and to study the potential functional role and molecular… read more here.
Keywords: expression; giant papillae; vkc; stromal lymphopoietin ... See more keywords
Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion
Sign Up to like & getrecommendations! Published in 2021 at "Science"
DOI: 10.1126/science.abd2893
Abstract: Sweat out the fat with TSLP! Thymic stromal lymphopoietin (TSLP) is a cytokine that can promote immune responses that characterize allergic diseases. Choa et al. found that mice engineered to produce elevated TSLP displayed selective… read more here.
Keywords: hypersecretion; sebum secretion; wat loss; tslp ... See more keywords
Emerging role for thymic stromal lymphopoietin–responsive regulatory T cells in colorectal cancer progression in humans and mice
Sign Up to like & getrecommendations! Published in 2022 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abl6960
Abstract: Recruitment of regulatory T cells (Tregs) to tumors is a hallmark of cancer progression. Tumor-derived factors, such as the cytokine thymic stromal lymphopoietin (TSLP), can influence Treg function in tumors. In our study, we identified… read more here.
Keywords: regulatory cells; tslp; progression; cancer progression ... See more keywords
Plasma thymic stromal lymphopoietin (TSLP) in adults with non-severe asthma: the EGEA study
Sign Up to like & getrecommendations! Published in 2022 at "Thorax"
DOI: 10.1136/thorax-2022-219192
Abstract: Thymic stromal lymphopoietin (TSLP), a cytokine involved in severe asthma treatment, was never studied in non-severe asthma. Among 969 adults from a large epidemiological study, cross-sectional analyses showed that plasma TSLP levels were associated with… read more here.
Keywords: tslp; asthma; non severe; thymic stromal ... See more keywords