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TSPAN12 (Tetraspanin 12) Is a Novel Negative Regulator of Aldosterone Production in Adrenal Physiology and Aldosterone-Producing Adenomas

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Published in 2022 at "Hypertension"

DOI: 10.1161/hypertensionaha.122.19783

Abstract: Background: Aldosterone-producing adenomas (APAs) are a major cause of primary aldosteronism, a condition of low-renin hypertension, in which aldosterone overproduction is usually driven by a somatic activating mutation in an ion pump or channel. TSPAN12… read more here.

Keywords: tspan12 tetraspanin; aldosterone producing; physiology; producing adenomas ... See more keywords