Synthesis of (‐)‐8a epi‐Lentiginosine via Tsuji‐Trost Reaction of d‐Glucose‐Derived Allylic Alcohols and Crystal Structure Analysis
Sign Up to like & getrecommendations! Published in 2025 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.202500103
Abstract: An indolizidine alkaloid, (‐)‐8a‐epi‐lentiginosine was synthesized from d‐glucose using the Pd‐BiPhePhos catalyzed intramolecular Tsuji‐Trost reaction of non‐derivatized allylic alcohol as a key construction of the hydroxylated pyrrolidine ring to give the desired product in good… read more here.
Keywords: epi lentiginosine; tsuji trost; crystal structure; structure ... See more keywords
Phase-transfer Tsuji—Trost allylation of CH-acids with the assistance of palladium complexes with bidentate PIII—N—PIII ligands
Sign Up to like & getrecommendations! Published in 2017 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-017-1788-6
Abstract: The Tsuji—Trost allylation of CH acids, in particular, those of the YCH2CO2Et type (Y = CO2Et, C(O)Me, CN), with allylic acetates in the K2CO3—DMF system in the presence of palladium catalysts with ligands RN(PPh2)2 (R… read more here.
Keywords: trost allylation; phase transfer; tsuji trost; allylation acids ... See more keywords
Stereoselective Synthesis of Fused Vinylcyclopropanes by Intramolecular Tsuji–Trost Cascade Cyclization
Sign Up to like & getrecommendations! Published in 2018 at "Organic Letters"
DOI: 10.1021/acs.orglett.8b02232
Abstract: A stereoselective intramolecular Tsuji–Trost cascade cyclization of (homo)allylic vicinal diacetates with a pendant β-ketoamide or related carbon nucleophile to give γ-lactam-fused vinylcyclopropanes is reported. In addition to two new rings, the products contain three new… read more here.
Keywords: cascade cyclization; fused vinylcyclopropanes; tsuji trost; trost cascade ... See more keywords
Interrupting Associative π-σ-π Isomerization Enables Z-Retentive Asymmetric Tsuji-Trost Reaction.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c15635
Abstract: The asymmetric Tsuji-Trost reaction has been extensively studied due to its importance in establishing stereogenic centers, often adjacent to an E-olefin moiety in organic molecules. The generally preferential formation of chiral E-olefin products is believed… read more here.
Keywords: associative isomerization; tsuji trost; asymmetric tsuji;
A novel intramolecular cyclization-induced fluorescent “turn-on” probe for detection of Pd2+ based on the Tsuji–Trost reaction
Sign Up to like & getrecommendations! Published in 2018 at "Analytical Methods"
DOI: 10.1039/c8ay00965a
Abstract: Palladium, as a toxic heavy metal, poses a great threat to the environment and human health. Therefore, it is essential to achieve the purpose of detecting trace amounts of palladium. In this paper, a probe… read more here.
Keywords: pd2; probe; based tsuji; trost reaction ... See more keywords
Enantioselective Synthesis of α-Chiral Sulfonates through Palladium-Catalyzed Tsuji-Trost Sulfonylation with Sulfur Dioxide
Sign Up to like & getrecommendations! Published in 2025 at "Organic Chemistry Frontiers"
DOI: 10.1039/d4qo01887g
Abstract: α-Chiral sulfonates have remained largely uncharted territory, primarily due to the intrinsic difficulties associated with achieving stereocontrol. In this study, we present an innovative three-component palladium-catalyzed asymmetric Tsuji-Trost sulfonylation protocol,... read more here.
Keywords: trost sulfonylation; tsuji trost; palladium catalyzed; chiral sulfonates ... See more keywords