Tetratricopeptide repeat domain 3 overexpression tends to form aggregates and inhibit ubiquitination and degradation of DNA polymerase γ
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DOI: 10.18632/oncotarget.22476
Abstract: Tetratricopeptide repeat (TPR) domain 3 (TTC3) is a protein that contains canonical RING finger and TPR motifs. It is encoded by the TTC3 gene located in the Down syndrome critical region (DSCR). In this study,… read more here.
Keywords: degradation; tetratricopeptide repeat; dna polymerase; ttc3 ... See more keywords