Combined 3D-QSAR, molecular docking and dynamics simulations studies to model and design TTK inhibitors
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DOI: 10.3389/fchem.2022.1003816
Abstract: Tyrosine threonine kinase (TTK) is the key component of the spindle assembly checkpoint (SAC) that ensures correct attachment of chromosomes to the mitotic spindle and thereby their precise segregation into daughter cells by phosphorylating specific… read more here.
Keywords: molecular docking; ttk inhibitors; combined qsar; design ... See more keywords