Low carbohydrate diets may increase risk of neural tube defects
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DOI: 10.1002/bdr2.1198
Abstract: Folic acid fortification significantly reduced the prevalence of neural tube defects (NTDs) in the United States. The popularity of “low carb” diets raises concern that women who intentionally avoid carbohydrates, thereby consuming fewer fortified foods,… read more here.
Keywords: tube defects; diets may; carbohydrate diets; neural tube ... See more keywords
Overview on neural tube defects: From development to physical characteristics
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DOI: 10.1002/bdr2.1380
Abstract: Neural tube defects (NTDs) are the second most common congenital malformations in humans affecting the development of the central nervous system. Although NTD pathogenesis has not yet been fully elucidated, many risk factors, both genetic… read more here.
Keywords: tube defects; neural tube; overview neural; defects development ... See more keywords
Summary of the 10th international conference on neural tube defects
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DOI: 10.1002/bdr2.1519
Abstract: Neural tube defects (NTDs) are birth defects that result from errors in the process of neurulation during development. The most frequent forms include anencephaly, which is fatal and involves damage to the developing brain, and… read more here.
Keywords: tube defects; research; tube; international conference ... See more keywords
Periconceptional folic acid use prevents both rare and common neural tube defects in China
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DOI: 10.1002/bdr2.1983
Abstract: Neural tube defects (NTDs) encompass a variety of distinct types. We assessed if the preventive effect of folic acid (FA) varied by NTD type and infant sex. read more here.
Keywords: periconceptional folic; tube defects; neural tube; folic acid ... See more keywords
Prevalence of neural tube defects in a rural area of north india from 2001 to 2014: A population-based survey.
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DOI: 10.1002/bdra.23578
Abstract: BACKGROUND Neural tube defects (NTDs) are one of the commonest birth defects. There was paucity of community-based data on occurrence of NTDs in India, especially from rural parts of the country. Against this background, the… read more here.
Keywords: tube defects; birth; prevalence; neural tube ... See more keywords
The interaction of maternal diabetes with mutations that affect folate metabolism and how they affect the development of neural tube defects in mice
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DOI: 10.1002/dvdy.92
Abstract: Abnormalities in maternal folate and carbohydrate metabolism have both been shown to induce neural tube defects (NTDs) in humans and animal models. Nevertheless, how these two factors might interact in the development of NTDs remains… read more here.
Keywords: tube defects; metabolism; interaction maternal; neural tube ... See more keywords
Identification of histone malonylation in the human fetal brain and implications for diabetes‐induced neural tube defects
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1403
Abstract: Neural tube defects (NTDs) are severe congenital malformations. Diabetes during pregnancy is a risk factor for NTDs, but its mechanism remains elusive. Emerging evidence suggests that protein malonylation is involved in diabetes. Here, we report… read more here.
Keywords: malonylation; tube defects; neural tube; identification histone ... See more keywords
Genetic mutations in ribosomal biogenesis gene TCOF1 identified in human neural tube defects
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.2150
Abstract: Rare mutations in multiple genes have been associated with human neural tube defects (NTDs), but their causative roles in NTDs disease are poorly understood. Insufficiency of the ribosomal biogenesis gene treacle ribosome biogenesis factor 1(Tcof1)… read more here.
Keywords: human neural; biogenesis; tube defects; tcof1 ... See more keywords
Mouse Models of Neural Tube Defects.
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DOI: 10.1007/978-981-15-2389-2_2
Abstract: During embryonic development, the central nervous system forms as the neural plate and then rolls into a tube in a complex morphogenetic process known as neurulation. Neural tube defects (NTDs) occur when neurulation fails and… read more here.
Keywords: tube defects; mouse models; tube; neural tube ... See more keywords
Acid folic and pregnancy: A mandatory supplementation.
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DOI: 10.1016/j.ando.2017.10.001
Abstract: Neural tube defects (NTD) occur in 0.5 to 2 per 1000 pregnancies with various handicaps for the affected child. It is now well established that folic acid deficiency (absolute or relative) is a predisposing factor… read more here.
Keywords: tube defects; folic acid; supplementation; folic pregnancy ... See more keywords
One carbon metabolism and folate transporter genes: Do they factor prominently in the genetic etiology of neural tube defects?
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DOI: 10.1016/j.biochi.2020.02.005
Abstract: Neural tube defects (NTDs) are a broad class of congenital birth defects that result from the failure of neural tube closure during neurulation. Folic acid supplementation has been shown to prevent the occurrence of NTDs… read more here.
Keywords: tube defects; neural tube; one carbon; etiology ... See more keywords