Design and development of macrocyclization methods for compounds with potential tuberculocidal activity to decrease CYP450 liver cytochrome inhibition
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DOI: 10.1134/s1070363217040107
Abstract: A procedure for macrocyclization of compounds with potential tuberculocidal activity was developed in order to obtaining compounds with a lower degree of inhibition of the key CYP 3A4 cytochrome. read more here.
Keywords: tuberculocidal activity; potential tuberculocidal; compounds potential; macrocyclization ... See more keywords