Articles with "tuberculosis" as a keyword



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Association of Mortality and Years of Potential Life Lost With Active Tuberculosis in the United States

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Published in 2020 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2020.14481

Abstract: This cohort study examines the risk of mortality and years of potential life lost among patients with active tuberculosis disease compared with individuals without active tuberculosis. read more here.

Keywords: mortality years; years potential; active tuberculosis; tuberculosis ... See more keywords
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In-Person vs Electronic Directly Observed Therapy for Tuberculosis Treatment Adherence

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Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2021.44210

Abstract: Key Points Question Is electronic directly observed therapy (DOT) noninferior to in-person DOT in supporting medication adherence for tuberculosis treatment? Findings In this randomized, 2-period crossover noninferiority trial of 216 patients with tuberculosis, the modified… read more here.

Keywords: tuberculosis; directly observed; electronic directly; dot ... See more keywords
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Clinicopathologic Features of Tuberculous Serpiginous-like Choroiditis.

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Published in 2018 at "JAMA ophthalmology"

DOI: 10.1001/jamaophthalmol.2017.5791

Abstract: Clinicopathologic Features of Tuberculous Serpiginous-like Choroiditis Serpiginous-like choroiditis (SLC) is a choroidal inflammation of diverse causes, which clinically resembles serpiginous choroiditis.1 Intraocular tuberculosis commonly presents as SLC in countries where Mycobacterium tuberculosis is endemic. In… read more here.

Keywords: choroiditis; serpiginous like; tuberculosis; like choroiditis ... See more keywords
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Sensitive and Feasible Specimen Collection and Testing Strategies for Diagnosing Tuberculosis in Young Children.

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Published in 2021 at "JAMA pediatrics"

DOI: 10.1001/jamapediatrics.2020.6069

Abstract: Importance Criterion-standard specimens for tuberculosis diagnosis in young children, gastric aspirate (GA) and induced sputum, are invasive and rarely collected in resource-limited settings. A far less invasive approach to tuberculosis diagnostic testing in children younger… read more here.

Keywords: reference; tuberculosis; sensitivity interdecile; yield ... See more keywords
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Synthesis, in vitro antibacterial activity against Mycobacterium tuberculosis, and reverse docking‐based target fishing of 1,4‐benzoxazin‐2‐one derivatives

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Published in 2021 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.202000199

Abstract: Seventeen 1,4‐benzoxazin‐2‐ones bearing the enaminone moiety and three of their analogs were tested for the antibacterial activity against Mycobacterium tuberculosis (H37Rv). Minimal bactericidal concentrations (MBCs) were determined after 41 days of incubation by BACTEC. 1,4‐Benzoxazin‐2‐ones… read more here.

Keywords: antibacterial activity; tuberculosis; activity mycobacterium; reverse docking ... See more keywords
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Drug re‐engineering and repurposing: A significant and rapid approach to tuberculosis drug discovery

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Published in 2022 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.202200214

Abstract: The prevalence of tuberculosis (TB) remains the leading cause of death from a single infectious agent, ranking it above all other contagious diseases. The problem to tackle this disease seems to become even worse due… read more here.

Keywords: drug discovery; tuberculosis; classes compounds; drug development ... See more keywords
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Expression of ESAT‐6 antigen from Mycobacterium tuberculosis in broccoli: An edible plant

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Published in 2020 at "Biotechnology and Applied Biochemistry"

DOI: 10.1002/bab.1867

Abstract: Tuberculosis (TB) is one of the major infectious diseases caused by Mycobacterium tuberculosis. The development of an effective and economical vaccine for controlling TB is essential especially for developing countries. Edible plants can serve as… read more here.

Keywords: tuberculosis; expression; antigen; vaccine ... See more keywords
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Domain wise differentiation of Mycobacterium tuberculosis H37 Rv hypothetical proteins: A roadmap to discover bacterial survival potentials.

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Published in 2021 at "Biotechnology and applied biochemistry"

DOI: 10.1002/bab.2109

Abstract: Proteomic information revealed approximately 3923 proteins in Mycobacterium tuberculosis H37 Rv (M. tuberculosis) genome of which around ∼25% of proteins are hypothetical proteins (HPs). The present work comprises computational approaches to identify and characterize the… read more here.

Keywords: hypothetical proteins; tuberculosis; hps; tuberculosis h37 ... See more keywords
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The pncA gene mutations of Mycobacterium tuberculosis in multidrug-resistant tuberculosis.

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Published in 2021 at "Biotechnology and applied biochemistry"

DOI: 10.1002/bab.2278

Abstract: The pncA gene encodes Pyrazinamidase enzyme which converts drug pyrazinamide to active form Pyrazinoic acid but mutations in this gene can prevent enzyme activity which leads to pyrazinamide resistance. The cross-sectional study was carried out… read more here.

Keywords: pnca gene; tuberculosis; multidrug resistant; gene ... See more keywords
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Preliminary Evaluation of Artemisinin–Cholesterol Conjugates as Potential Drugs for the Treatment of Intractable Forms of Malaria and Tuberculosis

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Published in 2018 at "ChemMedChem"

DOI: 10.1002/cmdc.201700579

Abstract: To evaluate the feasibility of developing drugs that may be active against both malaria and tuberculosis (TB) by using in part putative cholesterol transporters in the causative pathogens and through enhancement of passive diffusion in… read more here.

Keywords: artemisinin cholesterol; cholesterol; tuberculosis; malaria tuberculosis ... See more keywords
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Cutaneous nocardiosis with discharging sinus clinically mimicking tuberculosis diagnosed by cytology

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Published in 2019 at "Diagnostic Cytopathology"

DOI: 10.1002/dc.24217

Abstract: Nocardiosis is primarily a pulmonary infection commonly seen in immunocompromised individuals. However, lymphocutaneous nocardiosis is observed in immunocompetent individuals often after trauma. The clinical and cytomorphological features of lymphocutaneous nocardiosis closely mimic the most common… read more here.

Keywords: nocardiosis; cutaneous nocardiosis; cytology cutaneous; tuberculosis ... See more keywords