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Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.14481
Abstract: This cohort study examines the risk of mortality and years of potential life lost among patients with active tuberculosis disease compared with individuals without active tuberculosis.
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Keywords:
mortality years;
years potential;
active tuberculosis;
tuberculosis ... See more keywords
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Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.44210
Abstract: Key Points Question Is electronic directly observed therapy (DOT) noninferior to in-person DOT in supporting medication adherence for tuberculosis treatment? Findings In this randomized, 2-period crossover noninferiority trial of 216 patients with tuberculosis, the modified…
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Keywords:
tuberculosis;
directly observed;
electronic directly;
dot ... See more keywords
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Published in 2018 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2017.5791
Abstract: Clinicopathologic Features of Tuberculous Serpiginous-like Choroiditis Serpiginous-like choroiditis (SLC) is a choroidal inflammation of diverse causes, which clinically resembles serpiginous choroiditis.1 Intraocular tuberculosis commonly presents as SLC in countries where Mycobacterium tuberculosis is endemic. In…
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Keywords:
choroiditis;
serpiginous like;
tuberculosis;
like choroiditis ... See more keywords
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Published in 2021 at "JAMA pediatrics"
DOI: 10.1001/jamapediatrics.2020.6069
Abstract: Importance Criterion-standard specimens for tuberculosis diagnosis in young children, gastric aspirate (GA) and induced sputum, are invasive and rarely collected in resource-limited settings. A far less invasive approach to tuberculosis diagnostic testing in children younger…
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Keywords:
reference;
tuberculosis;
sensitivity interdecile;
yield ... See more keywords
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Published in 2021 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202000199
Abstract: Seventeen 1,4‐benzoxazin‐2‐ones bearing the enaminone moiety and three of their analogs were tested for the antibacterial activity against Mycobacterium tuberculosis (H37Rv). Minimal bactericidal concentrations (MBCs) were determined after 41 days of incubation by BACTEC. 1,4‐Benzoxazin‐2‐ones…
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Keywords:
antibacterial activity;
tuberculosis;
activity mycobacterium;
reverse docking ... See more keywords
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Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200214
Abstract: The prevalence of tuberculosis (TB) remains the leading cause of death from a single infectious agent, ranking it above all other contagious diseases. The problem to tackle this disease seems to become even worse due…
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Keywords:
drug discovery;
tuberculosis;
classes compounds;
drug development ... See more keywords
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Published in 2020 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1867
Abstract: Tuberculosis (TB) is one of the major infectious diseases caused by Mycobacterium tuberculosis. The development of an effective and economical vaccine for controlling TB is essential especially for developing countries. Edible plants can serve as…
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Keywords:
tuberculosis;
expression;
antigen;
vaccine ... See more keywords
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Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2109
Abstract: Proteomic information revealed approximately 3923 proteins in Mycobacterium tuberculosis H37 Rv (M. tuberculosis) genome of which around ∼25% of proteins are hypothetical proteins (HPs). The present work comprises computational approaches to identify and characterize the…
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Keywords:
hypothetical proteins;
tuberculosis;
hps;
tuberculosis h37 ... See more keywords
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Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2278
Abstract: The pncA gene encodes Pyrazinamidase enzyme which converts drug pyrazinamide to active form Pyrazinoic acid but mutations in this gene can prevent enzyme activity which leads to pyrazinamide resistance. The cross-sectional study was carried out…
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Keywords:
pnca gene;
tuberculosis;
multidrug resistant;
gene ... See more keywords
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Published in 2018 at "ChemMedChem"
DOI: 10.1002/cmdc.201700579
Abstract: To evaluate the feasibility of developing drugs that may be active against both malaria and tuberculosis (TB) by using in part putative cholesterol transporters in the causative pathogens and through enhancement of passive diffusion in…
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Keywords:
artemisinin cholesterol;
cholesterol;
tuberculosis;
malaria tuberculosis ... See more keywords
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Published in 2019 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.24217
Abstract: Nocardiosis is primarily a pulmonary infection commonly seen in immunocompromised individuals. However, lymphocutaneous nocardiosis is observed in immunocompetent individuals often after trauma. The clinical and cytomorphological features of lymphocutaneous nocardiosis closely mimic the most common…
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Keywords:
nocardiosis;
cutaneous nocardiosis;
cytology cutaneous;
tuberculosis ... See more keywords