Chronic Cavitary Infections Other than Tuberculosis: Clinical Aspects.
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DOI: 10.1097/rti.0000000000000345
Abstract: Lung cavitation may be due to infectious or noninfectious pathologic processes. The latter category includes nonmalignant conditions, such as granulomatosis with polyangiitis, and malignant conditions, such as squamous cell carcinoma of the lung. Infectious etiologies… read more here.
Keywords: cavitation; cause chronic; infections tuberculosis; tuberculosis clinical ... See more keywords
Mycobacterium tuberculosis clinical isolates carry mutational signatures of host immune environments.
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DOI: 10.1126/sciadv.aba4901
Abstract: Mycobacterium tuberculosis (Mtb) infection results in a spectrum of clinical and histopathologic manifestations. It has been proposed that the environmental and immune pressures associated with different contexts of infection have different consequences for the associated… read more here.
Keywords: isolates carry; carry mutational; tuberculosis; tuberculosis clinical ... See more keywords
Characterization of Genetic Variants Associated with Rifampicin Resistance Level in Mycobacterium tuberculosis Clinical Isolates Collected in Guangzhou Chest Hospital, China
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DOI: 10.2147/idr.s375869
Abstract: Objective Rifampicin (RIF)-resistance, a surrogate marker for multidrug-resistant tuberculosis (TB), is mediated by mutations in the rpoB gene. We aimed to investigate the prevalence of mutations pattern in the entire rpoB gene of Mycobacterium tuberculosis… read more here.
Keywords: clinical isolates; mycobacterium tuberculosis; resistance; characterization ... See more keywords
Determination of potentially novel compensatory mutations in rpoc associated with rifampin resistance and rpob mutations in Mycobacterium tuberculosis Clinical isolates from peru
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DOI: 10.4103/ijmy.ijmy_27_20
Abstract: Background: Rifampicin (RIF) resistance in Mycobacterium tuberculosis is frequently caused by mutations in the rpoB gene. These mutations are associated with a fitness cost, which can be overcome by compensatory mutations in other genes, among… read more here.
Keywords: tuberculosis; resistance; compensatory mutations; tuberculosis clinical ... See more keywords