The utility of pharmacokinetic studies for the evaluation of exposure-response relationships for standard dose anti-tuberculosis drugs.
Sign Up to like & getrecommendations! Published in 2018 at "Tuberculosis"
DOI: 10.1016/j.tube.2017.11.004
Abstract: Tuberculosis (TB) is a major public health problem. Many countries still fall below the minimum World Health Organization (WHO) TB treatment target success rate. There is conflicting evidence about whether concentrations of anti-tuberculosis drugs given… read more here.
Keywords: tuberculosis drugs; treatment; utility pharmacokinetic; tuberculosis ... See more keywords
Influence of HNF4α and HNF4α-AS1 gene variants on the risk of anti-tuberculosis drugs-induced hepatotoxicity.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of palliative medicine"
DOI: 10.21037/apm-21-2924
Abstract: BACKGROUND The most serious and common complication of the medication recommended by World Health Organization (WHO) for tuberculosis (TB) is anti-tuberculosis drugs-induced hepatotoxicity (ATDH). Pregnane X receptor (PXR) is a key factor of ATDH, while… read more here.
Keywords: hnf4 hnf4; anti tuberculosis; hnf4; hnf4 as1 ... See more keywords