High genetic diversity among Mycobacterium tuberculosis strains in Tehran, Iran
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Tuberculosis and Other Mycobacterial Diseases"
DOI: 10.1016/j.jctube.2018.01.001
Abstract: Introduction Tuberculosis (TB) still remains an important public health problem in Iran. The genotyping of Mycobacterium tuberculosis isolates is expected to lead to a better understanding of M. tuberculosis transmission in Tehran, the most populated… read more here.
Keywords: diversity among; high genetic; tuberculosis; tuberculosis isolates ... See more keywords
Mutations of rpoB, katG and inhA genes in multidrug-resistant Mycobacterium tuberculosis isolates from Zambia.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2020.02.026
Abstract: OBJECTIVES It is established that resistance to rifampicin (RIF) in 90% of the RIF resistantM. tuberculosis strains is attributable to point mutations in the rpoB gene while 50-95% of M. tuberculosis resistance to isoniazid (INH)… read more here.
Keywords: rpob katg; katg inha; tuberculosis; tuberculosis isolates ... See more keywords
A high throughput methodology for susceptibility testing of Mycobacterium tuberculosis isolates.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2018.02.001
Abstract: MICs for eleven anti-TB drugs with M. tuberculosis isolates were obtained by means of agar dilution with multi-point inoculation. The results were compared with classic agar dilution and the MTT assay. The multi-point inoculation method… read more here.
Keywords: methodology; susceptibility testing; agar dilution; tuberculosis isolates ... See more keywords
Subcultured Mycobacterium tuberculosis isolates on different growth media are fully representative of bacteria within clinical samples.
Sign Up to like & getrecommendations! Published in 2019 at "Tuberculosis"
DOI: 10.1016/j.tube.2019.05.001
Abstract: Mycobacterium tuberculosis (Mtb) whole genome sequencing (WGS) plays an increasingly important role in tuberculosis diagnosis and research. WGS is typically performed on biobanked isolates obtained by subculture during diagnosis. Genetic variation upon culturing is known… read more here.
Keywords: subcultured mycobacterium; mycobacterium tuberculosis; tuberculosis isolates; tuberculosis ... See more keywords
Molecular identification of mutations conferring resistance to rifampin, isoniazid and pyrazinamide among Mycobacterium tuberculosis isolates from Iran
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Chemotherapy"
DOI: 10.1080/1120009x.2020.1716479
Abstract: Here, we aimed to determine the susceptibility of 70 Mycobacterium tuberculosis isolates obtained from different regions of the country to 8 anti-tuberculosis (anti-TB) drugs and possible underlying mechanisms causing resistance to rifampin, isoniazid, and pyrazinamide.… read more here.
Keywords: mycobacterium tuberculosis; tuberculosis isolates; resistance; tuberculosis ... See more keywords
The 7H11 Agar Medium Supplemented with Calf Bovine Serum for Susceptibility Testing of Mycobacterium tuberculosis Isolates Against Pyrazinamide.
Sign Up to like & getrecommendations! Published in 2021 at "Microbial drug resistance"
DOI: 10.1089/mdr.2020.0509
Abstract: Despite its importance, pyrazinamide (PZA) is a blind spot in drug susceptibility testing in tuberculosis laboratories. The aim of this study was to set up a reliable agar-based proportion method for detection of PZA-resistant phenotypes… read more here.
Keywords: susceptibility testing; calf bovine; 7h11 agar; supplemented calf ... See more keywords
Fingerprinting of Mycobacterium tuberculosis isolates by MIRU-VNTR genotyping and detection of isoniazid resistance by real-time PCR.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medical microbiology"
DOI: 10.1099/jmm.0.001603
Abstract: Introduction. Tuberculosis (TB) is a great public health problem in developing countries such as Egypt. Genotyping of Mycobacterium tuberculosis isolates has a prominent role in the field of TB prevention.Aim. This study aimed to evaluate… read more here.
Keywords: tuberculosis; tuberculosis isolates; resistance; real time ... See more keywords
Fluoroquinolone susceptibility in first-line drug-susceptible M. tuberculosis isolates in Lima, Peru
Sign Up to like & getrecommendations! Published in 2021 at "BMC Research Notes"
DOI: 10.1186/s13104-021-05832-0
Abstract: Objective To determine at two distinct time points the prevalence of resistance to ofloxacin (OFX), the representative class drug of fluoroquinolones (FQs), in M. tuberculosis isolates susceptible to first-line drugs. Results There were 279 M.… read more here.
Keywords: drug; first line; line drug; tuberculosis isolates ... See more keywords
Genetic Diversity of Mycobacterium tuberculosis Isolates From an Amerindian Population in Chiapas, México
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.875909
Abstract: This is the first report of the genetic diversity of the Mycobacterium tuberculosis complex isolates found in a Mexican-Amerindian setting. In this study, we analyzed isolates collected from the Highlands region of Chiapas, Mexico, by… read more here.
Keywords: mycobacterium tuberculosis; tuberculosis; genetic diversity; tuberculosis isolates ... See more keywords
Phylogenetic relationships of Mycobacterium tuberculosis isolates in Poland: The emergence of Beijing genotype among multidrug-resistant cases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1161905
Abstract: Introduction The epidemiological situation of tuberculosis (TB) in Poland urges for its continuous and scrupulous monitoring. The objective of this study was to explore the genetic diversity of multidrug-resistant (MDR) and drug-susceptible (DS) Mycobacterium tuberculosis… read more here.
Keywords: poland; tuberculosis; isolates poland; beijing genotype ... See more keywords
Genomic characteristics of Mycobacterium tuberculosis isolates of cutaneous tuberculosis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1165916
Abstract: Objectives Cutaneous tuberculosis with various manifestations can be divided into several clinical types according to the host's immune status and infective route. However, the etiological factors of this disease remain unclear. The objective of this… read more here.
Keywords: mycobacterium tuberculosis; cutaneous tuberculosis; tuberculosis; tuberculosis isolates ... See more keywords