Articles with "tubule" as a keyword



Pincushion of Tubule Discovery and Tubular Morphology Landscape Establishment of Block Copolymer Self-Assemblies.

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Published in 2017 at "Macromolecular rapid communications"

DOI: 10.1002/marc.201700424

Abstract: Block copolymer (BCP) self-assembly is a versatile technique in the preparation of polymeric aggregates with varieties of morphologies. However, its morphology library is limited. Here, the discovery of pincushion of tubules is reported for the… read more here.

Keywords: block; block copolymer; self; self assemblies ... See more keywords

Human and rat renal proximal tubule in vitro models for ADME applications

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Published in 2025 at "Archives of Toxicology"

DOI: 10.1007/s00204-025-03987-4

Abstract: The kidney is a major organ dictating excretion rates of chemicals and their metabolites from the body and thus renal clearance is frequently a major component of pharmaco-(toxico)-kinetic profiles. Within the nephron, the proximal tubule… read more here.

Keywords: rat renal; culture; human rat; tubule ... See more keywords

Dentin sealing and antibacterial effects of silver-doped bioactive glass/mesoporous silica nanocomposite: an in vitro study

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Published in 2018 at "Clinical Oral Investigations"

DOI: 10.1007/s00784-018-2432-z

Abstract: ObjectivesTo synthesize a silver-doped bioactive glass/mesoporous silica nanoparticle (Ag-BGN@MSN), as well as to investigate its effects on dentinal tubule occlusion, microtensile bond strength (MTBS), and antibacterial activity.Materials and methodsAg-BGN@MSN was synthesized using a modified “quick… read more here.

Keywords: bgn msn; group; bgn; silver doped ... See more keywords
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Passivation and remediation of Pb and Cr in contaminated soil by sewage sludge biochar tubule

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Published in 2021 at "Environmental Science and Pollution Research"

DOI: 10.1007/s11356-021-14111-1

Abstract: Currently, numerous studies have carried out to research the effect of biochars remediation soil heavy metals (HMs) contaminated, but there have been fewer explorations of the effect of biochars tubule on soil HMs remediation. This… read more here.

Keywords: remediation; contaminated soil; soil; passivation remediation ... See more keywords

Transverse tubule remodelling: a cellular pathology driven by both sides of the plasmalemma?

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Published in 2017 at "Biophysical Reviews"

DOI: 10.1007/s12551-017-0273-7

Abstract: Transverse (t)-tubules are invaginations of the plasma membrane that form a complex network of ducts, 200–400 nm in diameter depending on the animal species, that penetrates deep within the cardiac myocyte, where they facilitate a fast… read more here.

Keywords: transverse tubule; pathology; cellular pathology; remodelling cellular ... See more keywords
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Molecular basis for epithelial morphogenesis and ion transport in the Malpighian tubule.

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Published in 2021 at "Current opinion in insect science"

DOI: 10.1016/j.cois.2021.02.001

Abstract: During development, the insect Malpighian tubule undergoes several programmed morphogenetic events that give rise to the tubule's ability to transport ions and water at unparalleled speed. Studies in Diptera, in particular, have greatly increased our… read more here.

Keywords: molecular basis; transport; morphogenesis; basis epithelial ... See more keywords

The Proximal Tubule Toxicity of Immunoglobulin Light Chains

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Published in 2021 at "Kidney International Reports"

DOI: 10.1016/j.ekir.2021.02.026

Abstract: Plasma and B cells dyscrasias that overproduce monoclonal immunoglobulin free light chains (FLCs) affect the kidney frequently in various ways. The hematologic dyscrasia responsible for the production of FLCs may or may not meet the… read more here.

Keywords: immunoglobulin; proximal tubule; light chains; tubule toxicity ... See more keywords

The Mn-motif protein MAP6d1 assembles ciliary doublet microtubules

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Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-61679-0

Abstract: Most eukaryotic cells have cilia that serve vital functions in sensing, signaling, motility. The core architecture of cilia is an array of microtubule doublets, which consist of a complete A-tubule and an incomplete B-tubule. The… read more here.

Keywords: doublet microtubules; map6d1 assembles; tubule; microtubule doublets ... See more keywords

High glucose–induced Smad3 linker phosphorylation and CCN2 expression are inhibited by dapagliflozin in a diabetic tubule epithelial cell model

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Published in 2021 at "Bioscience Reports"

DOI: 10.1042/bsr20203947

Abstract: Abstract Background: In the kidney glucose is freely filtered by the glomerulus and, mainly, reabsorbed by sodium glucose cotransporter 2 (SGLT2) expressed in the early proximal tubule. Human proximal tubule epithelial cells (PTECs) undergo pathological… read more here.

Keywords: glucose tgf; ccn2; glucose; tubule ... See more keywords

Epithelial tubule interconnection driven by HGF-Met signaling in the kidney

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Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2416887121

Abstract: Significance Our study identifies hepatocyte growth factor (HGF) as a key inducer of tubule anastomosis, the process where tubules connect to form a continuous network, in embryonic mouse kidneys. Through in vitro experiments using fluorescently… read more here.

Keywords: driven hgf; tubule; interconnection driven; tubule interconnection ... See more keywords

Clinical risk factors for kidney tubule biomarker abnormalities among hypertensive adults with reduced eGFR in the SPRINT trial.

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Published in 2022 at "American journal of hypertension"

DOI: 10.1093/ajh/hpac102

Abstract: BACKGROUND Urine biomarkers of kidney tubule health may distinguish aspects of kidney damage that cannot be captured by current glomerular measures. Associations of clinical risk factors with specific kidney tubule biomarkers have not been evaluated… read more here.

Keywords: higher levels; risk factors; kidney tubule; tubule ... See more keywords