Biomechanics of Endothelial Tubule Formation Differentially Modulated by Cerebral Cavernous Malformation Proteins
Sign Up to like & getrecommendations! Published in 2018 at "iScience"
DOI: 10.1016/j.isci.2018.11.001
Abstract: Summary At early stages of organismal development, endothelial cells self-organize into complex networks subsequently giving rise to mature blood vessels. The compromised collective behavior of endothelial cells leads to the development of a number of… read more here.
Keywords: biomechanics; tubule formation; cavernous malformation; cerebral cavernous ... See more keywords
Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-09262-6
Abstract: Peroxiredoxin1 (Prdx1) is an antioxidant enzyme belonging to the peroxiredoxin family of proteins. Prdx1 catalyzes the reduction of H2O2 and alkyl hydroperoxide and plays an important role in different biological processes. Prdx1 also participates in… read more here.
Keywords: pronephros development; proximal tubule; formation; acid wnt ... See more keywords
On the shuttling across the blood-brain barrier via tubule formation: Mechanism and cargo avidity bias
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abc4397
Abstract: Tubule formation acts as cargo transport across the blood-brain barrier. The blood-brain barrier is made of polarized brain endothelial cells (BECs) phenotypically conditioned by the central nervous system (CNS). Although transport across BECs is of… read more here.
Keywords: blood brain; avidity; formation; tubule formation ... See more keywords
MCM6 versus Ki-67 in diagnosis of luminal molecular subtypes of breast cancers
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostic Pathology"
DOI: 10.1186/s13000-022-01209-4
Abstract: Background Currently, breast cancers are divided into four major molecular subtypes. The distinction between the luminal A and luminal B subtypes is mainly based on the cellular proliferation indices and is assessed by the Ki-67… read more here.
Keywords: tubule formation; breast cancers; molecular subtypes; higher mcm6 ... See more keywords