Structural insights into tubulin detyrosination by vasohibins-SVBP complex
Sign Up to like & getrecommendations! Published in 2019 at "Cell Discovery"
DOI: 10.1038/s41421-019-0133-7
Abstract: Dear Editor, Microtubules are major elements of the cytoskeleton in eukaryotic cells, essential to a wide variety of cellular functions, including cell shape control, cell division, morphogenesis, motility, and motor protein-based intracellular transport. Microtubules are… read more here.
Keywords: svbp complex; vasohibins svbp; detyrosination; tubulin detyrosination ... See more keywords
Tubulin detyrosination promotes human trophoblast syncytium formation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjz084
Abstract: Abstract Human trophoblast syncytialization is one of the most important yet least understood events during placental development. In this study, we found that detyrosinated α-tubulin (detyr-α-tub), which is negatively regulated by tubulin tyrosine ligase (TTL),… read more here.
Keywords: tubulin detyrosination; ttl; human trophoblast; trophoblast ... See more keywords
Closing the tubulin detyrosination cycle
Sign Up to like & getrecommendations! Published in 2017 at "Science"
DOI: 10.1126/science.aar3895
Abstract: Enzymes that detyrosinate the microtubule cytoskeleton are identified Microtubules are cytoskeletal filaments that drive chromosome segregation during cell division, control cell shape and motility, and serve as rails for motor protein-based intracellular transport. Microtubules are… read more here.
Keywords: tubulin detyrosination; tubulin; detyrosination cycle; closing tubulin ... See more keywords