Novel diaryl-2H-azirines: Antitumor hybrids for dual-targeting tubulin and DNA.
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DOI: 10.1016/j.ejmech.2021.113256
Abstract: Multiple-target drugs may achieve better therapeutic effect via different pathways than single-target ones, especially for complex diseases. Tubulin and DNA are well-characterized molecular targets for anti-cancer drug development. A novel class of diaryl substituted 2H-azirines… read more here.
Keywords: novel diaryl; targeting tubulin; tubulin dna; dna ... See more keywords