Covalent binding of the organophosphate insecticide profenofos to tyrosine on α- and β-tubulin proteins.
Sign Up to like & getrecommendations! Published in 2018 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2018.02.003
Abstract: Organophosphorus (OP) compounds can bind covalently to many types of proteins and form protein adducts. These protein adducts can indicate the exposure to and neurotoxicity of OPs. In the present work, we studied adduction of… read more here.
Keywords: profenofos; tubulin proteins; insecticide profenofos; porcine tubulin ... See more keywords
The Loss of α- and β-Tubulin Proteins Are a Pathological Hallmark of Chronic Alcohol Consumption and Natural Brain Ageing
Sign Up to like & getrecommendations! Published in 2018 at "Brain Sciences"
DOI: 10.3390/brainsci8090175
Abstract: Repetitive excessive alcohol intoxication leads to neuronal damage and brain shrinkage. We examined cytoskeletal protein expression in human post-mortem tissue from Brodmann’s area 9 of the prefrontal cortex (PFC). Brain samples from 44 individuals were… read more here.
Keywords: tubulin proteins; hallmark chronic; chronic alcohol; tubulin ... See more keywords