Molecular mechanisms underlying microtubule growth dynamics
Sign Up to like & getrecommendations! Published in 2021 at "Current Biology"
DOI: 10.1016/j.cub.2021.02.035
Abstract: Microtubules are dynamic cytoskeletal filaments composed of αβ-tubulin heterodimers. Historically, the dynamics of single tubulin interactions at the growing microtubule tip have been inferred from steady-state growth kinetics. However, recent advances in the production of… read more here.
Keywords: microtubule; microtubule growth; tubulin tubulin; tubulin interactions ... See more keywords
The ring saga: looking back at the discovery of γ-tubulin and γ-tubulin ring complexes
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e22-07-0290
Abstract: For many years, two central, unanswered questions in cytoskeleton research were how microtubule assembly is nucleated and microtubule polarity established. The discoveries of γ-tubulin and γ-tubulin ring complexes were key advances that allowed these questions… read more here.
Keywords: tubulin ring; ring complexes; discovery tubulin; microtubule ... See more keywords
MICAL-L1 coordinates ciliogenesis by recruiting EHD1 to the primary cilium
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cell Science"
DOI: 10.1242/jcs.233973
Abstract: ABSTRACT The endocytic protein EHD1 plays an important role in ciliogenesis by facilitating fusion of the ciliary vesicle and removal of CP110 (also known as CCP110) from the mother centriole, as well as removal of… read more here.
Keywords: ciliogenesis; ehd1; tubulin tubulin; interaction ... See more keywords