Tudor-SN Promotes Early Replication of Dengue Virus in the Aedes aegypti Midgut
Sign Up to like & getrecommendations! Published in 2020 at "iScience"
DOI: 10.1016/j.isci.2020.100870
Abstract: Summary Diseases caused by mosquito-borne viruses have been on the rise for the last decades, and novel methods aiming to use laboratory-engineered mosquitoes that are incapable of carrying viruses have been developed to reduce pathogen… read more here.
Keywords: dengue virus; tudor; replication; aedes aegypti ... See more keywords
Protein components of ribonucleoprotein granules from Drosophila germ cells oligomerize and show distinct spatial organization during germline development
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-55747-x
Abstract: The assembly of large RNA-protein granules occurs in germ cells of many animals and these germ granules have provided a paradigm to study structure-functional aspects of similar structures in different cells. Germ granules in Drosophila… read more here.
Keywords: protein; germline development; granules drosophila; germ cells ... See more keywords
Phospho-Tudor-SN coordinates with STAT5 to regulate prolactin-stimulated milk protein synthesis and proliferation of bovine mammary epithelial cells.
Sign Up to like & getrecommendations! Published in 2021 at "Animal biotechnology"
DOI: 10.1080/10495398.2021.1879824
Abstract: Tudor staphylococcal nuclease (Tudor-SN) participates in milk synthesis and cell proliferation in response to prolactin (PRL) and plays a regulatory role on mTOR phosphorylation. However, the complicated molecular mechanism of Tudor-SN regulating milk protein synthesis… read more here.
Keywords: proliferation; tudor; protein synthesis; milk protein ... See more keywords
TIRR and 53BP1- partners in arms
Sign Up to like & getrecommendations! Published in 2017 at "Cell Cycle"
DOI: 10.1080/15384101.2017.1337966
Abstract: 53BP1 is a central player in the repair of DNA-double strand breaks (DSBs) as it orchestrates the choice between the DSB repair pathways, non-homologous end-joining (NHEJ) and homologous recombination (HR). 53BP1 promotes repair by NHEJ… read more here.
Keywords: recruitment; tirr 53bp1; brca1; tirr ... See more keywords
The Tudor protein Veneno assembles the ping-pong amplification complex that produces viral piRNAs in Aedes mosquitoes
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky1266
Abstract: Abstract PIWI-interacting RNAs (piRNAs) comprise a class of small RNAs best known for suppressing transposable elements in germline tissues. The vector mosquito Aedes aegypti encodes seven PIWI genes, four of which are somatically expressed. This… read more here.
Keywords: pong amplification; pirna; tudor; veneno assembles ... See more keywords
Tudor knockdown disrupts ovary development in Bactrocera dorsalis
Sign Up to like & getrecommendations! Published in 2019 at "Insect Molecular Biology"
DOI: 10.1111/imb.12533
Abstract: One of the main functions of the piwi‐interacting RNA pathway is the post‐transcriptional silencing of transposable elements in the germline of many species. In insects, proteins belonging to the Tudor superfamily proteins belonging to the… read more here.
Keywords: ovary development; bactrocera dorsalis; tudor; role ... See more keywords
Tudor-SN–mediated endonucleolytic decay of human cell microRNAs promotes G1/S phase transition
Sign Up to like & getrecommendations! Published in 2017 at "Science"
DOI: 10.1126/science.aai9372
Abstract: Breaking down miRNAs Although much work has examined microRNA (miRNA) biogenesis, relatively little is known about miRNA decay. Elbarbary et al. now identify Tudor-SN, an endonuclease that interacts with the RNA-induced silencing complex. Tudor-SN targets… read more here.
Keywords: decay; phase transition; tudor; mirna decay ... See more keywords