LAUSR

Risk of Melanoma Recurrence After Diagnosis of a High-Risk Primary Tumor.

Sign Up to like & get
recommendations!
0 Published in 2019 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2019.0440

Abstract: Importance With emerging new systemic treatments for metastatic melanoma, early detection of disease recurrence is increasingly important. Objective To investigate the risk of melanoma recurrence in patients with a localized melanoma at a high risk… read more here.

Keywords: tumor; risk; recurrence; ajcc ... See more keywords

Development of a Model to Estimate the Association Between Delay in Cancer Treatment and Local Tumor Control and Risk of Metastases

Sign Up to like & get
recommendations!
2 Published in 2021 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2020.34065

Abstract: Key Points Question What are the potential risks of decreased local tumor control and increased metastatic spread for patients with cancer who experience treatment delays due to the coronavirus disease 2019 (COVID-19) pandemic? Findings In… read more here.

Keywords: treatment; model; tumor control; local tumor ... See more keywords

Open Access Information Added.

Sign Up to like & get
recommendations!
1 Published in 2018 at "JAMA oncology"

DOI: 10.1001/jamaoncol.2017.4703

Abstract: globulins stimulated by humoral immunity has been shown to activate FCγRs and promote neoplastic progression through interaction with myeloid cells in a model of squamous cell carcinoma.3 Macrophages express high levels of activating FCγRs, are… read more here.

Keywords: access information; open access; tumor cells; information added ... See more keywords

Potential of Aqueous Humor as a Surrogate Tumor Biopsy for Retinoblastoma

Sign Up to like & get
recommendations!
0 Published in 2017 at "JAMA Ophthalmology"

DOI: 10.1001/jamaophthalmol.2017.4097

Abstract: Importance Retinoblastoma (Rb) is one of the first tumors to have a known genetic etiology. However, because biopsy of this tumor is contraindicated, it has not been possible to define the effects of secondary genetic… read more here.

Keywords: copy number; dna; aqueous humor; tumor derived ... See more keywords

Anterior Approach vs Conventional Hepatectomy for Resection of Colorectal Liver Metastasis: A Randomized Clinical Trial.

Sign Up to like & get
recommendations!
0 Published in 2020 at "JAMA surgery"

DOI: 10.1001/jamasurg.2020.5050

Abstract: Importance Tumor relapse after partial hepatectomy for colorectal liver metastasis (CRLM) remains an unsolved issue. Intraoperative manipulation of the liver during conventional hepatectomy might enhance hematogenous tumor cell spread. The anterior approach is an alternative… read more here.

Keywords: conventional hepatectomy; anterior approach; resection; tumor ... See more keywords

Characterization of single circulating tumor cells

Sign Up to like & get
recommendations!
0 Published in 2017 at "FEBS Letters"

DOI: 10.1002/1873-3468.12662

Abstract: “Liquid biopsy” has been introduced for the analysis of circulating tumor cells (CTCs) in the blood of cancer patients, and this new diagnostic approach has received enormous attention. CTCs are derived from primary tumors and… read more here.

Keywords: tumor cells; single circulating; circulating tumor; characterization single ... See more keywords

Linear ubiquitination‐induced necrotic tumor remodeling elicits immune evasion

Sign Up to like & get
recommendations!
2 Published in 2023 at "FEBS Letters"

DOI: 10.1002/1873-3468.14623

Abstract: Tumor‐elicited inflammation confers tumorigenic properties, including cell death resistance, proliferation, or immune evasion. To focus on inflammatory signaling in tumors, we investigated linear ubiquitination, which enhances the nuclear factor‐κB signaling pathway and prevents extrinsic programmed… read more here.

Keywords: immune evasion; ubiquitination induced; linear ubiquitination; tumor ... See more keywords

FBXW7 deletion contributes to lung tumor development and confers resistance to gefitinib therapy

Sign Up to like & get
recommendations!
0 Published in 2018 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12200

Abstract: Gefitinib, an epidermal growth factor receptor–tyrosine kinase inhibitor (EGFR‐TKI), is an effective treatment for non‐small‐cell lung cancer (NSCLC) with EGFR activating mutations, but inevitably, the clinical efficacy is impeded by the emergence of acquired resistance.… read more here.

Keywords: tumor development; gefitinib; lung tumor; therapy ... See more keywords

Exosomal microRNAs as tumor markers in epithelial ovarian cancer

Sign Up to like & get
recommendations!
0 Published in 2018 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12371

Abstract: Specific microRNAs (miRNAs) are packaged in exosomes that regulate processes in tumor development and progression. The current study focuses on the influence of exosomal miRNAs in the pathogenesis of epithelial ovarian cancer (EOC). MiRNA profiles… read more here.

Keywords: epithelial ovarian; mir; mir 200b; ovarian cancer ... See more keywords

Human cancer evolution in the context of a human immune system in mice

Sign Up to like & get
recommendations!
1 Published in 2018 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12374

Abstract: Immunotherapy is one of the most promising cancer treatment modalities, but the lack of appropriate preclinical in vivo models hampers the development of novel immunotherapeutic strategies. Here, we studied the ability of transplanted human cancer… read more here.

Keywords: human cancer; system mice; immune system; cancer ... See more keywords

High affinity binding of H3K14ac through collaboration of bromodomains 2, 4 and 5 is critical for the molecular and tumor suppressor functions of PBRM1

Sign Up to like & get
recommendations!
1 Published in 2019 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12434

Abstract: Polybromo‐1 (PBRM1) is an important tumor suppressor in kidney cancer. It contains six tandem bromodomains (BDs), which are specialized structures that recognize acetyl‐lysine residues. While BD2 has been found to bind acetylated histone H3 lysine… read more here.

Keywords: tumor suppressor; molecular tumor; binding h3k14ac; tumor ... See more keywords