Abstract 2930: ADG153, a novel masked anti-CD47 IgG1 SAFEbody, demonstrates strong in vivo anti-tumor activities in preclinical solid tumor models and preferential CD47 target engagement in the tumor microenvironment
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DOI: 10.1158/1538-7445.am2023-2930
Abstract: Background: Anti-CD47 therapies have demonstrated promising clinical activities; however, expression of CD47 on many different normal human cell types, including RBCs, serves as a large antigen sink for anti-CD47 antibodies. Blocking CD47 on RBCs, such… read more here.
Keywords: anti tumor; anti cd47; tumor activities; cd47 ... See more keywords
pH Sensitive Triptolide-Loaded Liposome Calcium Phosphate Nanoparticles Exhibit Enhanced Anti-Tumor Activities Against Ovarian Cancer Without Damaging the Reproductive System.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2017.2429
Abstract: Triptolide (TP), a diterpenoid triepoxide purified from the Chinese traditional medicine Tripterygium wilfordii Hook F (TWHF), possesses potent anti-tumor activities against several malignancies, including ovarian cancer. However, its short half-life in circulation and severe reproductive… read more here.
Keywords: calcium phosphate; anti tumor; tumor activities; ovarian cancer ... See more keywords
Anti-tumor activities of probiotics in cervical cancer
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DOI: 10.1186/s13048-020-00668-x
Abstract: Cervical cancer is considered as an important malignancy among women worldwide. Currently-used treatments of cervical cancer are reported to be cytotoxic for patients. Moreover, these therapies have shown some side effects which can negatively affect… read more here.
Keywords: activities probiotics; cervical cancer; anti tumor; tumor activities ... See more keywords
Polysaccharides as Potential Anti-tumor Biomacromolecules —A Review
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DOI: 10.3389/fnut.2022.838179
Abstract: Cancer, as one of the most life-threatening diseases, has attracted the attention of researchers to develop drugs with minimal side effects. The bioactive macromolecules, such as the polysaccharides, are considered the potential candidates against cancer… read more here.
Keywords: anti tumor; tumor biomacromolecules; tumor activities; polysaccharides potential ... See more keywords