Monte Carlo-derived 99mTc uptake quantification with commercial planar MBI: absolute tumor activity.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.16196
Abstract: BACKGROUND Molecular breast imaging (MBI) of 99m Tc-sestamibi is an emerging adjunct qualitative tool in the detection and diagnosis of breast cancer. PURPOSE This work outlines the development and performance evaluation of a methodology to… read more here.
Keywords: monte carlo; methodology; tumor; tumor activity ... See more keywords
CRISPR knock out CTLA-4 enhances the anti-tumor activity of cytotoxic T lymphocytes.
Sign Up to like & getrecommendations! Published in 2017 at "Gene"
DOI: 10.1016/j.gene.2017.09.010
Abstract: T cell-mediated anti-tumor immunity plays a pivotal role in cancer immune surveillance. Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a protein receptor mainly expressed in activated T cells and regulatory T cells. CTLA-4 competes with CD28… read more here.
Keywords: tumor activity; cytotoxic; ctla; anti tumor ... See more keywords
The anti-tumor activity of exopolysaccharides from Pseudomonas strains against HT-29 colorectal cancer cell line.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.01.268
Abstract: The anti-tumor activity of extracted exopolysaccharides (EPSs) (without any side effects) of Pseudomonas aeruginosa on HT-29 colorectal cancer cell line has not been previously investigated. The extraction and partial characterization of EPS from the strains… read more here.
Keywords: tumor activity; colorectal cancer; anti tumor; cancer cell ... See more keywords
Anti-tumor activity and related mechanism study of Bacillus Polymyxa transformed Panax ginseng C. A. Mey
Sign Up to like & getrecommendations! Published in 2018 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2018.06.013
Abstract: Abstract Panax ginseng C. A. Mey has a history of drug use for thousands of years, and ginsenoside is the main active ingredient. Whether the conversion products of ginseng by Bacillus polymyxa can enhance the… read more here.
Keywords: tumor; tumor activity; ginseng; anti tumor ... See more keywords
Effect of doxorubicin release rate from polyethylene glycol-modified liposome on anti-tumor activity in B16-BL6 tumor-bearing mice.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2021.11.020
Abstract: To investigate the effect of doxorubicin (DOX) release rates from polyethylene glycol (PEG)-liposomes on the anti-tumor activity, several in-vitro and in-vivo studies were performed by utilizing three types of DOX-PEG-liposomes showing the slow (L-Slow), middle… read more here.
Keywords: tumor; tumor activity; release; mice ... See more keywords
Synthesis and anti-tumor activity of derivatives of ring A of asiatic acid
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2019.1616693
Abstract: Abstract Based on the simulation of the docking of survivin protein with known small molecule inhibitors, the active groups which can bind to target proteins were analyzed by the techniques of computer-aided drug design (CADD).… read more here.
Keywords: ring asiatic; tumor activity; anti tumor; synthesis anti ... See more keywords
The natural product chitosan enhances the anti-tumor activity of natural killer cells by activating dendritic cells
Sign Up to like & getrecommendations! Published in 2018 at "OncoImmunology"
DOI: 10.1080/2162402x.2018.1431085
Abstract: ABSTRACT Natural products comprise an important class of biologically active molecules. Many of these compounds derived from natural sources exhibit specific physiologic or biochemical effects. An example of a natural product is chitosan, which is… read more here.
Keywords: product chitosan; tumor activity; chitosan; anti tumor ... See more keywords
EXTH-20. SYNGENEIC B7-H3-SPECIFIC CAR T-CELLS HAVE POTENT ANTI-BRAIN TUMOR ACTIVITY VIA LOCAL OR SYSTEMIC DELIVERY
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa215.374
Abstract: We and others have identified B7-H3 (CD276) as a promising target for CAR T-cell-based immunotherapies for pediatric brain tumors. So far, B7-H3-CAR T cells have only been studied in xenograft models for brain tumors, which… read more here.
Keywords: tumor activity; car cells; brain; car ... See more keywords
SURGICAL OUTCOMES OF VASOPROLIFERATIVE RETINAL TUMORS' REFRACTORY TO NONINVASIVE THERAPIES
Sign Up to like & getrecommendations! Published in 2022 at "Retina"
DOI: 10.1097/iae.0000000000003520
Abstract: Purpose: To evaluate the outcomes of surgical treatment of refractory vasoproliferative retinal tumors (VPTs) and its complications. Methods: Clinical charts of all patients diagnosed with VPTs who underwent surgical treatment from 2005 to 2020 were… read more here.
Keywords: best corrected; vasoproliferative retinal; retinal tumors; tumor activity ... See more keywords
Abstract 5151: Nanoliposomal irinotecan (nal-IRI, MM-398) has greater anti-tumor activity than topotecan and irinotecan in mouse models of small cell lung cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-5151
Abstract: Nal-IRI, a liposomal formulation of irinotecan, is designed for extended circulation relative to non-liposomal irinotecan and to exploit leaky tumor vasculature for enhanced drug delivery to tumors. Following tumor deposition, nal-IRI is taken up by… read more here.
Keywords: nal iri; anti tumor; tumor activity; tumor ... See more keywords
Abstract 2935: ZW270, a conditionally masked IL-12 cytokine fusion protein displaying potent anti-tumor activity absent systemic toxicity
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2935
Abstract: IL-12 is a pleiotropic cytokine that potently stimulates anti-tumor cytotoxic T and NK cell mediated immunity. Recombinant IL-12 reduces tumor growth in multiple mouse models, but its therapeutic application has been limited by severe toxicities.… read more here.
Keywords: potency; anti tumor; att 12fc; tumor activity ... See more keywords