Downregulation of m6A writer complex member METTL14 in bladder urothelial carcinoma suppresses tumor aggressiveness
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DOI: 10.1002/1878-0261.13181
Abstract: N6‐methyladenosine (m6A) and its regulatory proteins have been associated with tumorigenesis in several cancer types. However, knowledge on the mechanistic network related to m6A in bladder cancer (BlCa) is rather limited, requiring further investigation of… read more here.
Keywords: writer complex; m6a; tumor aggressiveness; m6a writer ... See more keywords
Dynamic contrast‐enhanced MRI model selection for predicting tumor aggressiveness in papillary thyroid cancers
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DOI: 10.1002/nbm.4166
Abstract: The purpose of this study was to identify the optimal tracer kinetic model from T1‐weighted dynamic contrast‐enhanced magnetic resonance imaging (DCE‐MRI) data and evaluate whether parameters estimated from the optimal model predict tumor aggressiveness determined… read more here.
Keywords: papillary thyroid; model; dynamic contrast; contrast enhanced ... See more keywords
Loss of nectin‐3 expression as a marker of tumor aggressiveness in pancreatic neuroendocrine tumor
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DOI: 10.1111/pin.12881
Abstract: Pancreatic neuroendocrine tumors (PanNETs) are rare, and prediction of aggressive characteristics, such as recurrence and metastasis and prognosis of PanNETs remain difficult. Nectins are cell adhesion molecules that regulate the formation of adherens and tight… read more here.
Keywords: nectin expression; tumor aggressiveness; pancreatic neuroendocrine; tumor ... See more keywords
Monopolar Spindle 1 Kinase (MPS1/TTK) mRNA Expression is Associated with Earlier Development of Clinical Symptoms, Tumor Aggressiveness and Survival of Glioma Patients
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DOI: 10.3390/biomedicines8070192
Abstract: Inhibition of the protein kinase MPS1, a mitotic spindle-checkpoint regulator, reinforces the effects of multiple therapies against glioblastoma multiforme (GBM) in experimental settings. We analyzed MPS1 mRNA-expression in gliomas WHO grade II, III and in… read more here.
Keywords: mps1; mrna expression; tumor aggressiveness; tumor ... See more keywords
Omega-6 Polyunsaturated Fatty Acids Enhance Tumor Aggressiveness in Experimental Lung Cancer Model: Important Role of Oxylipins
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DOI: 10.3390/ijms23116179
Abstract: Lung cancer is currently the leading cause of cancer death worldwide; it is often diagnosed at an advanced stage and bears poor prognosis. It has been shown that diet is an important environmental factor that… read more here.
Keywords: lung cancer; important role; tumor; tumor aggressiveness ... See more keywords