ITGA5 promotes tumor angiogenesis in cervical cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5873
Abstract: Integrins are critical to cancer progression. Integrin alpha 5 (ITGA5) is correlated with the prognosis of cervical cancer patients. However, whether ITGA5 plays an active role in cervical cancer progression or not remains unknown. read more here.
Keywords: cervical cancer; promotes tumor; itga5 promotes; tumor angiogenesis ... See more keywords
C‐X‐C motif chemokine receptor 4 promotes tumor angiogenesis in gastric cancer via activation of JAK2/STAT3
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biology International"
DOI: 10.1002/cbin.10794
Abstract: C‐X‐C motif chemokine receptor 4 (CXCR4) overexpression promotes gastric cancer growth and metastasis. In this study, we determined its role in regulating tumor angiogenesis. We overexpressed CXCR4 in gastric cancer cells and examined the effects… read more here.
Keywords: gastric cancer; stat3; cancer; tumor angiogenesis ... See more keywords
Lymphotoxin‐α promotes tumor angiogenesis in HNSCC by modulating glycolysis in a PFKFB3‐dependent manner
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32221
Abstract: Tumor angiogenesis is critical for tumor progression as the new blood vessels supply nutrients and facilitate metastasis. Previous studies indicate tumor associated lymphocytes, including B cells and T cells, contribute to tumor angiogenesis and tumor… read more here.
Keywords: hnscc; pfkfb3 dependent; angiogenesis; tumor angiogenesis ... See more keywords
Effect and mechanism of circRNAs in tumor angiogenesis and clinical application.
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DOI: 10.1002/ijc.33863
Abstract: Tumor blood vessels provide oxygen and necessary nutrients for the tumor, which provides the basis for tumor metastasis. Therefore, tumor angiogenesis plays a very important role in tumor growth and metastasis. In contrast to linear… read more here.
Keywords: effect mechanism; clinical application; tumor angiogenesis; tumor ... See more keywords
Clinically relevant concentrations of lidocaine inhibit tumor angiogenesis through suppressing VEGF/VEGFR2 signaling
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-019-03815-4
Abstract: BackgroundAngiogenesis, the formation of blood vessel, is required for invasive tumor growth and metastasis. In this study, the effects of lidocaine, an amide-link local anesthetic, on angiogenesis and tumor growth were investigated.MethodsIn vitro angiogenesis assays… read more here.
Keywords: angiogenesis; cell; lidocaine; growth ... See more keywords
Ropivacaine inhibits tumor angiogenesis via sodium-channel-independent mitochondrial dysfunction and oxidative stress
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bioenergetics and Biomembranes"
DOI: 10.1007/s10863-019-09793-9
Abstract: The anti-cancer role of local anesthetics has garnered attention in recent years because increasing evidence show that local anesthetics reduce the risk of tumor metastasis and recurrence. Angiogenesis, the formation of new blood vessels, is… read more here.
Keywords: tumor; angiogenesis; ropivacaine inhibits; tumor angiogenesis ... See more keywords
Aspirin suppresses tumor cell-induced angiogenesis and their incongruity
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cell Communication and Signaling"
DOI: 10.1007/s12079-018-00499-y
Abstract: Tumor neovascularization/tumor angiogenesis is a pathophysiological process in which new blood vessels are formed from existing blood vessels in the primary tumors to supply adequate oxygen and nutrition to cancer cells for their proliferation and… read more here.
Keywords: angiogenesis; asa; endothelial cells; cell ... See more keywords
Fentanyl stimulates tumor angiogenesis via activating multiple pro-angiogenic signaling pathways.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.08.038
Abstract: Angiogenesis plays a vital role in tumor progression and metastasis. To better understand the role of anesthesia in tumor biology, we previously reported that bupivacaine displayed the inhibitory effects in endothelial cells. In this work,… read more here.
Keywords: signaling pathways; pro angiogenic; angiogenesis; multiple pro ... See more keywords
Propofol inhibits tumor angiogenesis through targeting VEGF/VEGFR and mTOR/eIF4E signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.03.094
Abstract: Propofol, a commonly used intravenous anesthetic in tumor surgery, has recently garnered attention for its anti-cancer activity. We previously demonstrated that propofol inhibits migration and invasion of esophageal squamous cell carcinoma cells. However, the effects… read more here.
Keywords: endothelial cells; mtor eif4e; propofol inhibits; tumor angiogenesis ... See more keywords
Proteoglycan signaling in tumor angiogenesis and endothelial cell autophagy.
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2019.05.003
Abstract: The need for more effective cancer therapies is omnipresent as the ever-complex, and highly adaptive, mechanisms of tumor biology allow this disease to elude even the most stringent treatment options. The expanding field of proteoglycan… read more here.
Keywords: tumor angiogenesis; signaling tumor; biology; proteoglycan signaling ... See more keywords
NSD2 promotes tumor angiogenesis through methylating and activating STAT3 protein
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DOI: 10.1038/s41388-021-01747-z
Abstract: Tumor angiogenesis plays vital roles in tumorigenesis and development; regulatory mechanism of angiogenesis is still not been fully elucidated. NSD2, a histone methyltransferase catalyzing di-methylation of histone H3 at lysine 36, has been proved a… read more here.
Keywords: methylation; angiogenesis; stat3; nsd2 promotes ... See more keywords