Enhanced anti‐tumor and anti‐metastasis efficacy against breast cancer with an intratumoral injectable phospholipids‐based phase separation gel co‐loaded with 5‐fluotouracil and magnesium oxide by neutralizing acidic microenvironment
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.05.072
Abstract: Graphical abstract Figure. No caption available. ABSTRACT Traditional chemotherapy against breast cancer usually accompanied with metastasis. Thus, it is significant to enhance anti‐tumor and anti‐metastasis efficacy simultaneously. The extracellular environment of most tumors is acidic… read more here.
Keywords: tumor; metastasis efficacy; anti metastasis; metastasis ... See more keywords
Unlocking the potential of iridium and ruthenium arene complexes as anti-tumor and anti-metastasis chemotherapeutic agents.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of inorganic biochemistry"
DOI: 10.2139/ssrn.4223287
Abstract: It is a major challenge to design novel multifunctional metal-based chemotherapeutic agents for anti-tumor and anti-metastasis applications. Two complexes (OA-Ir and OA-Ru) were synthesized via CuAAC (copper-catalyzed azide-alkyne cycloaddition) reaction from nontoxic Ir-N3 or Ru-N3… read more here.
Keywords: metastasis; anti tumor; tumor anti; arene ... See more keywords
Anti-tumor and Anti-angiogenic Ergosterols from Ganoderma lucidum
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2017.00085
Abstract: This study was carried out to isolate chemical constituents from the lipid enriched fraction of Ganoderma lucidum extract and to evaluate their anti-proliferative effect on tumor cells and human umbilical vein endothelial cells (HUVECs). Ergosterol… read more here.
Keywords: tumor; tumor cells; anti tumor; cells huvecs ... See more keywords