Association of Social Determinants and Tumor Biology With Racial Disparity in Survival From Early-Stage, Hormone-Dependent Breast Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.7705
Abstract: Importance Black women with hormone receptor-positive breast cancer experience the greatest racial disparity in survival of all breast cancer subtypes. The relative contributions of social determinants of health and tumor biology to this disparity are… read more here.
Keywords: tumor biology; breast; disparity; breast cancer ... See more keywords
Centromere Protein F in Tumor Biology: Cancer's Achilles Heel
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Medicine"
DOI: 10.1002/cam4.70949
Abstract: Centromere protein F (CENP‐F) is an important nuclear matrix protein that regulates mitosis and the cell cycle, and plays a crucial role in recruiting spindle checkpoint proteins to maintain the accuracy of chromosome segregation. Studies… read more here.
Keywords: centromere protein; biology cancer; protein tumor; biology ... See more keywords
The mRECIST Classification Provides Insight into Tumor Biology for Patients With Hepatocellular Carcinoma Awaiting Liver Transplantation
Sign Up to like & getrecommendations! Published in 2019 at "Liver Transplantation"
DOI: 10.1002/lt.25333
Abstract: With recent changes in United Network for Organ Sharing policy, patients in the United States with hepatocellular carcinoma (HCC) are likely to spend more time on the liver transplantation (LT) waiting list. The increasing wait… read more here.
Keywords: hepatocellular carcinoma; lrt; tumor biology; liver transplantation ... See more keywords
Prognostic and Therapeutic Implications of Tumor Biology, Including Gene Alterations, in Colorectal Liver Metastases
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-021-04962-x
Abstract: For patients with colorectal liver metastases (CLM), the combination of surgical resection with other therapeutic options is essential. This article shows how recent advances in knowledge of tumor biology, including genetic alterations, affect the choice… read more here.
Keywords: tumor biology; colorectal liver; biology including; biology ... See more keywords
Internally Controlled and Dynamic Optical Measures of Functional Tumor Biology
Sign Up to like & getrecommendations! Published in 2022 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.2c05450
Abstract: Imaging defined aspects of functional tumor biology with bioluminescent reporter transgenes is a popular approach amongst the research community in drug development, as it is sensitive, relatively high-throughput and low cost. However, the lack of… read more here.
Keywords: measures functional; tumor biology; internally controlled; tumor ... See more keywords
CMET-11. IMPACT OF TUMOR SIZE AND MOLECULAR PROFILE ON LOCAL CONTROL IN PATIENTS WITH BREAST CANCER BRAIN METASTASES: UNDERSTANDING TUMOR BIOLOGY AND RADIOSURGERY DOSING
Sign Up to like & getrecommendations! Published in 2017 at "Neuro-oncology"
DOI: 10.1093/neuonc/nox168.160
Abstract: INTRODUCTION Studies in the breast cancer literature have demonstrated that recurrence rates after surgery and adjuvant whole-breast irradiation differ based on tumor subtype. The hypothesis of this study was to clarify the relationship between tumor… read more here.
Keywords: tumor biology; breast cancer; cancer brain; biology ... See more keywords
Investigating the Impact of Tumor Biology and Social Determinants on Time to Diagnosis and Stage at Presentation of Wilms Tumor
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000002846
Abstract: Delays in diagnosis and time to diagnosis generally are used interchangeably in cancer disparity research, but these terms may have important differences. Although these terms are related, we hypothesize that time to diagnosis is determined… read more here.
Keywords: time diagnosis; stage; biology; tumor ... See more keywords
Abstract 1904: Somatic copy number alterations and gene expression signatures are associated with aggressive tumor biology in African Americans and European Americans with renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1904
Abstract: Background: Renal cell carcinoma (RCC) is the deadliest of all urologic cancers in the US. RCC survival is highly dependent on histology. Survival rates range between 55-60% for clear cell RCC (ccRCC) and 80-90% for… read more here.
Keywords: gene expression; gene; biology; tumor biology ... See more keywords
Abstract 3576: Socio-environmental exposure leads to disparities in colorectal cancer mortality and tumor biology in metropolitan Detroit
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-3576
Abstract: Non-Hispanic Black (NHB) patients face the highest colorectal cancer (CRC) mortality rates in the US, heavily influenced by social determinants of health (SDOH). Neighborhood quality, a key SDOH, impacts both socioeconomic factors and exposure to… read more here.
Keywords: colorectal cancer; cancer; socio environmental; mortality ... See more keywords
Primary Cilia in Tumor Biology: The Primary Cilium as a Therapeutic Target in Cholangiocarcinoma.
Sign Up to like & getrecommendations! Published in 2017 at "Current drug targets"
DOI: 10.2174/1389450116666150223162737
Abstract: Cilia are microtubule-based organelles, which are ubiquitously expressed in epithelial cells. Cholangiocytes, the epithelial cells lining the biliary tree, have primary cilia extending from their apical plasma membrane into the ductal lumen, where the cilia… read more here.
Keywords: tumor biology; cholangiocarcinoma; biology; primary cilia ... See more keywords
Current advances in the diagnosis and personalized treatment of breast cancer: lessons from tumor biology.
Sign Up to like & getrecommendations! Published in 2020 at "Personalized medicine"
DOI: 10.2217/pme-2020-0070
Abstract: Breast cancer treatment has advanced enormously in the last decade. Most of this is due to advances reached in the knowledge regarding tumor biology, mainly in the field of diagnosis and treatment. This review brings… read more here.
Keywords: treatment; biology; tumor biology; breast cancer ... See more keywords