Anti-tumor effects of anti-PD-1 antibody, pembrolizumab, in humanized NSG PDX mice xenografted with dedifferentiated liposarcoma.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.02.042
Abstract: The efficacy of an immune checkpoint blockade has been demonstrated against various types of cancer, but its suitability has not been fully proven for therapies specifically targeting sarcoma. We conducted a pan-cancer tumor data analysis… read more here.
Keywords: anti antibody; mice xenografted; xenografted dedifferentiated; tumor effects ... See more keywords
ER-mediated anti-tumor effects of shikonin on breast cancer.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172667
Abstract: Estrogen receptor (ER) is expressed in most Breast cancer (BC) patients. G protein-coupled estrogen receptor (GPER), which is a membrane-bound estrogen receptor, is associated with the tumor development and progression in BC. Shikonin (SK) is… read more here.
Keywords: estrogen; breast cancer; tumor effects; anti tumor ... See more keywords
Overview of Silibinin anti-tumor effects
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Herbal Medicine"
DOI: 10.1016/j.hermed.2020.100375
Abstract: Abstract Silibinin is a major component of Silymarin mixture (Silybum marianum), which has traditionally been used to treat a wide range of liver diseases. Recently, Silibinin and its flavonoid derivatives in several in vitro models… read more here.
Keywords: silibinin anti; overview silibinin; tumor effects; anti tumor ... See more keywords
Anti-tumor effects of (1→3)-β-d-glucan from Saccharomyces cerevisiae in S180 tumor-bearing mice.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2016.10.106
Abstract: (1→3)-β-d-Glucan from Saccharomyces cerevisiae is a typical polysaccharide with various biological effects and is considered a candidate for the prevention and treatment of cancer in vitro. Research into the function of (1→3)-β-d-glucan in tumor-bearing animals… read more here.
Keywords: tumor bearing; s180 tumor; tumor effects; anti tumor ... See more keywords
Estrogen receptor β exhibited anti-tumor effects on osteosarcoma cells by regulating integrin, IAP, NF-kB/BCL-2 and PI3K/Akt signal pathway
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bone Oncology"
DOI: 10.1016/j.jbo.2017.09.005
Abstract: This study aimed to investigate the effects of Estrogen receptor β (ERβ) on osteosarcoma cells, and explore the regulatory mechanisms involved in this process. Osteosarcoma U2-OS cells consisted four groups, and treated by E2, E2… read more here.
Keywords: iap; tumor effects; anti tumor; osteosarcoma cells ... See more keywords
A light-facilitated drug delivery system from a pseudo-protein/hyaluronic acid nanocomplex with improved anti-tumor effects.
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale"
DOI: 10.1039/c9nr01909j
Abstract: Reduction-sensitive nanomedicine is a promising strategy to achieve controlled release of payloads in response to intracellular reductive milieu. However, endolysosomal sequestration of internalized carriers and insufficient redox potential in endolysosomes may delay the release of… read more here.
Keywords: tumor effects; anti tumor; tumor; delivery ... See more keywords
2-methoxyestradiol inhibits melanoma cell growth by activating adaptive immunity.
Sign Up to like & getrecommendations! Published in 2022 at "Immunopharmacology and immunotoxicology"
DOI: 10.1080/08923973.2022.2062380
Abstract: Background: The overall survival of melanoma patients remains poor despite advancements in surgical treatment and targeted therapies. Therefore, there is a need to develop new therapeutic strategies for melanoma. 2-methoxyestradiol (2-ME) is a major metabolite… read more here.
Keywords: tumor effects; anti tumor; methoxyestradiol inhibits; melanoma ... See more keywords
Stereotactic body radiation therapy and thymosin alpha-1-induced anti-tumor effects in heavily pretreated, metastatic esophageal squamous cell carcinoma patients
Sign Up to like & getrecommendations! Published in 2018 at "OncoImmunology"
DOI: 10.1080/2162402x.2018.1450128
Abstract: ABSTRACT This study investigated the anti-tumor effects of stereotactic body radiation therapy (SBRT) with thymosin alpha-1 (Tα1) in heavily pretreated, metastatic esophageal squamous cell carcinoma (mESCC) patients. Thirty-one patients with at least 2 metastatic sites… read more here.
Keywords: tumor; heavily pretreated; tumor effects; anti tumor ... See more keywords
Enhancing conventional chemotherapy drug cisplatin-induced anti-tumor effects on human gastric cancer cells both in vitro and in vivo by Thymoquinone targeting PTEN gene
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.20721
Abstract: Combination chemotherapy regimen with several anti-tumor drugs is a strategy to improve outcome. Thymoquinone (TQ) has been reported to exert biological activity on various types of human cancers without obvious toxicity. However, only few studies… read more here.
Keywords: gastric cancer; cisplatin; tumor effects; anti tumor ... See more keywords
MicroRNA-383: A tumor suppressor miRNA in human cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.955486
Abstract: Downregulated expression of anti-tumor miR-383 has been found in many kinds of cancer. MiR-383 family members can directly target the 3′-untranslated region (3′-UTR) of the mRNA of some pro-tumor genes to attenuate several cancer-related processes,… read more here.
Keywords: anti tumor; tumor effects; pro tumor; mir 383 ... See more keywords
NFYA promotes the anti-tumor effects of gluconeogenesis in hepatocellular carcinoma through the regulation of PCK1 expression
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.983599
Abstract: Reprogramming of glucose metabolism occurs in many human tumor types, and one of these, gluconeogenesis, is known to exhibit anti-tumor effects in hepatocellular carcinoma (HCC). The transcription factor NFYA regulates gluconeogenesis in the normal liver… read more here.
Keywords: hepatocellular carcinoma; anti tumor; tumor effects; gluconeogenesis ... See more keywords