Light Metabolically Reprograms CD8+ T Cells to Potentiate STING-Driven Tumor Eradication and Prevent Metastasis.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202515121
Abstract: Immunotherapy remains ineffective in many solid tumors due to poor T‐cell infiltration and a metabolically suppressive tumor microenvironment. A dual strategy combining low‐level light (LLL) therapy with a nanoscale stimulator of interferon genes (STING) agonist… read more here.
Keywords: tumor eradication; cd8; tumor; cell ... See more keywords
The tumor static exposure (TSE) concept & utility: Application to combination treatment of radiation and radiosensitizing agent in tumor xenograft experiments
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz268.102
Abstract: Abstract Background We present a pharmacodynamic model that describes the tumor volume evolution during and after treatment with radiation and in combination with a radiosensitizing agent. A key contribution is the inclusion of a long-term… read more here.
Keywords: tumor; tumor eradication; treatment; model ... See more keywords