Accurate Identification of Subclones in Tumor Genomes
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DOI: 10.1093/molbev/msac136
Abstract: Abstract Understanding intratumor heterogeneity is critical for studying tumorigenesis and designing personalized treatments. To decompose the mixed cell population in a tumor, subclones are inferred computationally based on variant allele frequency (VAF) from bulk sequencing… read more here.
Keywords: accurate identification; subclones tumor; sequencing data; tumor genomes ... See more keywords