Reply to Dr. Witjes regarding universal tumor genomic sequencing as a prescreen for germline genetic testing in patients diagnosed with ovarian cancer
Sign Up to like & getrecommendations! Published in 2021 at "Gynecologic Oncology Reports"
DOI: 10.1016/j.gore.2021.100843
Abstract: We would like to thank Dr. Witjes and her colleagues for their interest in our paper and for taking the time to elaborate on the promises of universal tumor genomic sequencing as a prescreen for… read more here.
Keywords: tumor; genetic testing; germline testing; tumor genomic ... See more keywords
Psychological impact of comprehensive tumor genomic profiling results for advanced cancer patients.
Sign Up to like & getrecommendations! Published in 2022 at "Patient education and counseling"
DOI: 10.1016/j.pec.2022.01.011
Abstract: OBJECTIVE Comprehensive tumor genomic profiling (CTGP) is increasingly used to personalize treatments, providing hope, but potentially disappointment, for patients. We explored psychological outcomes in patients with advanced, incurable cancer, after receiving CTGP results. METHODS Participants… read more here.
Keywords: cancer; comprehensive tumor; actionable results; advanced cancer ... See more keywords
Abstract 3121: Exercise and tumor genomic landscapes in 2,879 patients with cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3121
Abstract: Approximately two-thirds of cancer diagnoses globally are attributed to modifiable lifestyle factors such as smoking, diet and inactivity. Conversely, regular exercise is linked to decreased risk of multiple cancers. However, the underlying molecular mechanisms are… read more here.
Keywords: tumor genomic; genomic landscapes; tumor; exercise ... See more keywords
Tumor Genomic Testing: Identifying Characteristics Associated With Germline Risk for Developing Malignancy.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical journal of oncology nursing"
DOI: 10.1188/20.cjon.623-626
Abstract: Tumor genomic testing is used primarily to facilitate the selection of the best possible treatment for a malignancy based on the genomic characteristics of the tumor. Germline genomic testing has implications for care and recommendations… read more here.
Keywords: tumor genomic; germline risk; genomic testing; malignancy ... See more keywords
The impact of tumor genomic profile on the effectiveness of adjuvant chemotherapy in resectable intrahepatic cholangiocarcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.4_suppl.474
Abstract: 474Background: The incidence and mortality of ICC is rising in the U.S. While surgical resection currently offers the only potential for cure, the role of adjuvant chemotherapy is not well defined.... read more here.
Keywords: chemotherapy; adjuvant chemotherapy; impact tumor; tumor genomic ... See more keywords
Tumor genomic analysis for biomarker identification in a phase I trial of the Wee 1 inhibitor adavosertib (AZD1775).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.3624
Abstract: 3624Background: Adavosertib, a first-in-class Wee1 kinase inhibitor, abrogates G2/M cell cycle arrest causing premature mitosis and DNA replication stress, yielding enhanced DNA damage. Here we rep... read more here.
Keywords: inhibitor; analysis biomarker; identification phase; biomarker identification ... See more keywords
Radiogenomics of neuroblastomas: Relationships between imaging phenotypes, tumor genomic profile and survival
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0185190
Abstract: Purpose This study investigated relationships between neuroblastomas (NBs) imaging phenotypes, tumor genomic profile and patient outcome. Patients and methods This IRB-approved retrospective observational study included 133 NB patients (73 M, 60 F; median age 15… read more here.
Keywords: imaging phenotypes; tumor genomic; genomic profile; survival ... See more keywords