HIPK2 role in the tumor–host interaction: Impact on fibroblasts transdifferentiation CAF‐like
Sign Up to like & getrecommendations! Published in 2019 at "Iubmb Life"
DOI: 10.1002/iub.2144
Abstract: The dialogue between cancer cells and the surrounding fibroblasts, tumor‐associated macrophages (TAM), and immune cells can create a tumor microenvironment (TME) able to promote tumor progression and metastasis and induce resistance to anticancer therapies. Cancer… read more here.
Keywords: host interaction; transdifferentiation; cancer cells; cancer ... See more keywords
Nonlinear studies of tumor morphological stability using a two-fluid flow model
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DOI: 10.1007/s00285-018-1212-3
Abstract: We consider the nonlinear dynamics of an avascular tumor at the tissue scale using a two-fluid flow Stokes model, where the viscosity of the tumor and host microenvironment may be different. The viscosities reflect the… read more here.
Keywords: fluid flow; two fluid; morphological stability; using two ... See more keywords
A map of tumor–host interactions in glioma at single-cell resolution
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DOI: 10.1093/gigascience/giaa109
Abstract: ABSTRACT Background Single-cell RNA sequencing is the reference technique for characterizing the heterogeneity of the tumor microenvironment. The composition of the various cell types making up the microenvironment can significantly affect the way in which… read more here.
Keywords: single cell; interactions glioma; tumor host; cell ... See more keywords
Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1–Independent Manner
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-22-0439
Abstract: CKLF-like MARVEL transmembrane domain-containing 6 (CMTM6) has been identified as a regulator of membranal programmed death ligand 1 (PD-L1) stability and a factor associated with malignancy progression, but the effects and mechanisms of CMTM6 on… read more here.
Keywords: cytotoxicity; tumor host; cmtm6; suppression ... See more keywords