A thiopyrylium salt for PET/NIR‐II tumor imaging and image‐guided surgery
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12674
Abstract: All tumor imaging modalities have resolution limits below which deeply situated small metastatic foci may not be identified. Moreover, incomplete lesion excision will affect the outcomes of the patients. Scintigraphy is adept in locating lesions,… read more here.
Keywords: thiopyrylium salt; pet; tumor imaging; tumor ... See more keywords
Tumor Microenvironment-Triggered Aggregation of Antiphagocytosis 99m Tc-Labeled Fe3 O4 Nanoprobes for Enhanced Tumor Imaging In Vivo.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced materials"
DOI: 10.1002/adma.201701095
Abstract: A tumor microenvironment responsive nanoprobe is developed for enhanced tumor imaging through in situ crosslinking of the Fe3 O4 nanoparticles modified with a responsive peptide sequence in which a tumor-specific Arg-Gly-Asp peptide for tumor targeting… read more here.
Keywords: tumor microenvironment; enhanced tumor; fe3; tumor imaging ... See more keywords
High-Specificity In Vivo Tumor Imaging Using Bioorthogonal NIR-IIb Nanoparticles.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202102950
Abstract: Lanthanide-based NIR-IIb nanoprobes are ideal for in vivo imaging. However, existing NIR-IIb nanoprobes often suffer from low tumor-targeting specificity, limiting their widespread use. Here the application of bioorthogonal nanoprobes with high tumor-targeting specificity for in… read more here.
Keywords: nir iib; tumor imaging; specificity vivo; tumor ... See more keywords
Enhancing the Contrast of Tumor Imaging for Image-Guided Surgery Using a Tumor-Targeting Probiotic with the Continuous Expression of a Biomarker.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01200
Abstract: Tumor recurrence commonly results from tumor-positive resection margins and metastatic lesions. The complete removal of tumor-positive margins is particularly essential in clinics. Thus, we designed a strategy based on Escherichia coli Nissle 1917 (EcN) nitroreductase… read more here.
Keywords: tumor imaging; tumor targeting; ecn ntr; tumor ... See more keywords
Synthesis and Preclinical Evaluation of Novel 99mTc-Labeled Glucose Derivatives Containing Different Proline Analogs as Linker Moieties for Tumor Imaging.
Sign Up to like & getrecommendations! Published in 2025 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.5c01046
Abstract: 2-[18F]Fluoro-2-deoxy-d-glucose ([18F]FDG) is the most extensively utilized tumor imaging agent in clinical positron emission tomography (PET) applications. Nevertheless, no radiolabeled glucose derivatives for single-photon emission computed tomography (SPECT) imaging have achieved clinical usage comparable to… read more here.
Keywords: glucose derivatives; tumor imaging; 99mtc labeled; different proline ... See more keywords
A pH-Responsive Covalent Nanoscale Device Enhancing Temporal and Force Stability for Specific Tumor Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "Nano letters"
DOI: 10.1021/acs.nanolett.2c03487
Abstract: Approaches to DNA probe-mediated precision medicine have been extensively explored for the diagnosis and treatment of diverse types of cancer. Despite this, simple nanoscale devices with the required recognition specificity and sensitivity for clinical application… read more here.
Keywords: nanoscale device; driven covalent; tumor imaging; covalent nanoscale ... See more keywords
Ultrasmall MnSe Nanoparticles as T1-MRI Contrast Agents for In Vivo Tumor Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c25101
Abstract: Magnetic resonance imaging (MRI) has excellent potential in the clinical monitoring of tumors because it can provide high-resolution soft tissue imaging. However, commercial contrast agents (CAs) used in MRI still have some problems such as… read more here.
Keywords: mnse; contrast agents; tumor imaging; ultrasmall mnse ... See more keywords
Intelligent Dual-Lock Deoxyribonucleic Acid Automatons Boosting Precise Tumor Imaging.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c20024
Abstract: An early and accurate cancer diagnosis holds the potential to improve treatment and prognosis. Nevertheless, the complexity of the biological system limits the selectivity of existing approaches and makes tumor imaging in vivo particularly challenging.… read more here.
Keywords: intelligent dual; lock deoxyribonucleic; deoxyribonucleic acid; tumor imaging ... See more keywords
Emissive Lipid Nanoparticles as Biophotonic Contrast Agent for Site-Selective Solid Tumor Imaging in Pre-Clinical Models.
Sign Up to like & getrecommendations! Published in 2024 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.4c08273
Abstract: Small organic dye-based fluorescent agents are highly potent in solid tumor imaging but face challenges such as poor photostability, nonspecific distribution, low circulation, and weak tumor binding. Nanocarriers overcome these issues with better physicochemical and… read more here.
Keywords: tumor imaging; contrast; site; tumor ... See more keywords
Erythrocyte Membrane-Coated Upconversion Nanoparticles with Minimal Protein Adsorption for Enhanced Tumor Imaging.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.6b14450
Abstract: Upconversion nanoparticles (UCNPs) with superior optical and chemical features have been broadly employed for in vivo cancer imaging. Generally, UCNPs are surface modified with ligands for cancer active targeting. However, nanoparticles in biological fluids are… read more here.
Keywords: upconversion nanoparticles; tumor imaging; membrane; rbc ucnps ... See more keywords
Optical Characteristics and Tumor Imaging Capabilities of Near Infrared Dyes in Free and Nano-Encapsulated Formulations Comprised of Viral Capsids.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b03373
Abstract: Near infrared (NIR) fluorescent molecules and nanosized structures can serve as potential optical probes for image-guided removal of small tumor nodules (≲ 1 mm diameter). Although indocyanine green (ICG) remains as the only FDA-approved NIR… read more here.
Keywords: nano encapsulated; imaging capabilities; near infrared; brcy106 nhs ... See more keywords