Tumor‐Induced Osteomalacia: Treatment Progress Using Burosumab, an Anti‐FGF23 Monoclonal Antibody
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4280
Abstract: I n this issue of JBMR, Jan de Beur and colleagues (1) report the primary analysis and findings up to closure of their prospective, open-label, single-arm, phase 2 study (NCT02304367) to evaluate the safety and… read more here.
Keywords: treatment; tumor induced; tio; induced osteomalacia ... See more keywords
Clinical Challenges in Diagnosis, Tumor Localization and Treatment of Tumor‐Induced Osteomalacia: Outcome of a Retrospective Surveillance
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4620
Abstract: Tumor‐induced osteomalacia (TIO) is an acquired fibroblast growth factor 23 (FGF23)‐related hypophosphatemic osteomalacia caused by phosphaturic mesenchymal tumors (PMTs) developed in the bone or soft tissue. Diagnostic delay should be addressed, and ideal techniques to… read more here.
Keywords: tumor induced; tomography; induced osteomalacia; treatment ... See more keywords
Tumor-induced osteomalacia in association with PTEN-negative Cowden syndrome
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DOI: 10.1007/s00198-017-4372-x
Abstract: Tumor-induced osteomalacia (TIO) is a rare paraneoplastic condition in which phosphaturic mesenchymal tumors (PMTs) secrete high levels of fibroblast growth factor 23 (FGF23) into the circulation. This results in renal phosphate wasting, hypophosphatemia, muscle weakness,… read more here.
Keywords: cowden syndrome; tumor induced; tio; induced osteomalacia ... See more keywords
Tumor-Induced Osteomalacia
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DOI: 10.1007/s00223-020-00691-6
Abstract: Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by tumoral production of fibroblast growth factor 23 (FGF23). The hallmark biochemical features include hypophosphatemia due to renal phosphate wasting, inappropriately normal or frankly low 1,25-dihydroxy-vitamin… read more here.
Keywords: fgf23; tumor induced; tio; induced osteomalacia ... See more keywords
Epidemiology of Tumor-Induced Osteomalacia in Denmark
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DOI: 10.1007/s00223-021-00843-2
Abstract: Tumor-induced osteomalacia (TIO) is a rare, acquired condition of phosphate wasting due to phosphaturic mesenchymal tumors. Because the incidence and prevalence of TIO is unknown, we conducted an observational cohort study using national Danish health… read more here.
Keywords: per 100; 100 000; tumor induced; tio ... See more keywords
Ameloblastic Fibroodontoma of Mandible Causing Tumor Induced Osteomalacia: A Case Report with Review of 88 Phosphaturic Oral Neoplasms
Sign Up to like & getrecommendations! Published in 2021 at "Head and Neck Pathology"
DOI: 10.1007/s12105-020-01267-4
Abstract: Tumor induced osteomalacia (TIO) is a rare paraneoplastic syndrome associated with tumors secreting fibroblast growth factor 23, which induces osteomalacia. Microscopically, these tumors most commonly show benign phosphaturic mesenchymal tumors. We report the first case… read more here.
Keywords: case; tumor induced; oral neoplasms; induced osteomalacia ... See more keywords
Diagnostic performance of 68Ga-DOTATOC PET/CT in tumor-induced osteomalacia
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DOI: 10.1007/s12149-021-01575-x
Abstract: Tumor-induced osteomalacia (TIO) is caused by typically small tumors that secrete fibroblast growth factor 23 (FGF23). As tumor resection is the only effective treatment for TIO, it is important to detect the culprit tumor. We… read more here.
Keywords: dotatoc pet; 68ga dotatoc; dotatoc; tumor induced ... See more keywords
A Biomechanical Model of Tumor-Induced Intracranial Pressure and Edema in Brain Tissue.
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DOI: 10.1016/j.bpj.2019.02.030
Abstract: Brain tumor growth and tumor-induced edema result in increased intracranial pressure (ICP), which, in turn, is responsible for conditions as benign as headaches and vomiting or as severe as seizures, neurological damage, or even death.… read more here.
Keywords: tissue; tumor induced; model; brain ... See more keywords
FGF-23 transmitted tumor – induced hypophosphatemic osteomalacia: A rare case of a young woman with recurrent fractures and review of the literature
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone Oncology"
DOI: 10.1016/j.jbo.2022.100413
Abstract: Highlights • Tumor-transmitted osteomalacia is a rare FGF 23 transmitted phosphaturic disease.• Delay of diagnosis is common due to small and clinically silent underlying tumors.• The most sensitive imaging modality is 68Ga-DOTA-TOC-PET/CT-scan.• Complete resection of… read more here.
Keywords: tumor; fgf transmitted; tumor induced; osteomalacia rare ... See more keywords
Surgical treatment of secondary trigeminal neuralgia induced by cerebellopontine angle tumors: A single-center experience.
Sign Up to like & getrecommendations! Published in 2020 at "World neurosurgery"
DOI: 10.1016/j.wneu.2020.05.226
Abstract: OBJECTIVE Secondary trigeminal neuralgia (TN) caused by cerebellopontine angle (CPA) tumors are rare. However, TN may be a primary manifestation in the neurosurgery department. In this study, we aimed to retrospectively assess patients with CPA… read more here.
Keywords: single center; tumor induced; trigeminal neuralgia; cerebellopontine angle ... See more keywords
Sunitinib represses regulatory T cells to overcome immunotolerance in a murine model of hepatocellular cancer
Sign Up to like & getrecommendations! Published in 2017 at "OncoImmunology"
DOI: 10.1080/2162402x.2017.1372079
Abstract: ABSTRACT Successful development of immunotherapeutic strategies for hepatocellular cancer (HCC) has been impeded by limited understanding of tumor-induced profound tolerance and lack of a clinically faithful HCC model. Recently, we developed a novel model that… read more here.
Keywords: hcc; hepatocellular cancer; sunitinib; tumor induced ... See more keywords