Association Between Metastatic Melanoma Response to Checkpoint Inhibitor Therapy and Tumor-Infiltrating Lymphocyte Classification on Primary Cutaneous Melanoma Biopsies.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.4959
Abstract: This cohort study examines the association between tumor-infiltrating lymphocyte classification and disease progression among patients with metastatic primary cutaneous melanoma receiving checkpoint inhibitor therapy. read more here.
Keywords: tumor infiltrating; melanoma; primary cutaneous; cutaneous melanoma ... See more keywords
Assessing the Prognostic Significance of Tumor-Infiltrating Lymphocytes in Patients With Melanoma Using Pathologic Features Identified by Natural Language Processing
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.26337
Abstract: Key Points Question Are tumor-infiltrating lymphocytes (TILs) an independent prognostic factor for overall survival among patients with primary cutaneous melanoma? Findings This cohort study identified clinical and histopathologic characteristics of 14 436 patients with cutaneous melanoma… read more here.
Keywords: infiltrating lymphocytes; natural language; tumor infiltrating; melanoma using ... See more keywords
Awakening Allies for Breaking Microenvironment Barriers: NIR-II Guided Orthogonal Activation of Tumor-infiltrating Mast Cells for Efficient Nano-drug Delivery.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300420
Abstract: Mast cells (MCs), powerful immune cells that heavily infiltrate cancer cells, play a crucial role in tumor formation. Activated MCs can release histamine and a family of proteases through degranulation effects, concurrently achieving endothelial junction… read more here.
Keywords: tumor infiltrating; activation tumor; mast cells; tumor ... See more keywords
The landscape of immune microenvironment in lung adenocarcinoma and squamous cell carcinoma based on PD‐L1 expression and tumor‐infiltrating lymphocytes
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2580
Abstract: The aim of this study was to investigate the tumor microenvironment immune types (TMIT) based on tumor cell programmed cell death ligand 1 (PD‐L1) expression and tumor‐infiltrating lymphocytes (TILs) distribution and whether distinct TMIT subtypes… read more here.
Keywords: lung adenocarcinoma; infiltrating lymphocytes; expression tumor; tumor infiltrating ... See more keywords
Lumpectomy followed by radiation improves survival in HER2 positive and triple‐negative breast cancer with high tumor‐infiltrating lymphocytes compared to mastectomy alone
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.4050
Abstract: The goal was to compare the 5‐year DFS and 5‐year OS in patients with early‐stage human epidermal growth factor receptor 2 breast cancer (HER2+ BC) and triple‐negative breast cancer (TNBC) in relation to the amount… read more here.
Keywords: negative breast; breast; breast cancer; tumor infiltrating ... See more keywords
Peripheral and tumor‐infiltrating immune cells are correlated with patient outcomes in ovarian cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5590
Abstract: At present, there is still a lack of reliable biomarkers for ovarian cancer (OC) to guide prognosis prediction and accurately evaluate the dominant population of immunotherapy. In recent years, the relationship between peripheral blood markers… read more here.
Keywords: tumor infiltrating; ovarian cancer; peripheral tumor; immune cells ... See more keywords
Is the presence of tumor‐infiltrating lymphocytes predictive of outcomes in patients with melanoma?
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34013
Abstract: The significance of tumor‐infiltrating lymphocytes (TILs) in melanoma is debated. This article presents a multicenter, retrospective study assessing the predictive and prognostic value of TILs. read more here.
Keywords: tumor infiltrating; infiltrating lymphocytes; predictive outcomes; lymphocytes predictive ... See more keywords
Tumor‐infiltrating lymphocytes in breast FNA biopsy cytology: A predictor of tumor‐infiltrating lymphocytes in histologic evaluation
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22551
Abstract: Tumor‐infiltrating lymphocytes (TILs) are associated with various clinicopathological features. Using cytologic specimens for assessing TILs remains to be established. This retrospective study aimed to establish a practical method to assess TILs in cytologic samples. read more here.
Keywords: lymphocytes breast; tumor infiltrating; infiltrating lymphocytes; cytology ... See more keywords
Heat shock protein 70 and tumor‐infiltrating NK cells as prognostic indicators for patients with squamous cell carcinoma of the head and neck after radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK‐ROG)
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31213
Abstract: Tumor cells frequently overexpress heat shock protein 70 (Hsp70) and present it on their cell surface, where it can be recognized by pre‐activated NK cells. In our retrospective study the expression of Hsp70 was determined… read more here.
Keywords: tumor infiltrating; oncology; hsp70 expression;
Combining the guidelines-method and multiphoton imaging method to improve the prognostic value of tumor-infiltrating lymphocytes in breast cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biophotonics"
DOI: 10.1002/jbio.202300060
Abstract: Multiphoton microscopy (MPM) was introduced to label-freely obtain tumor-infiltrating lymphocytes (TILs) images from a total of 611 patients, and the prognostic value of TILs in breast cancer was assessed by the MPM method (TILs-MPM) and… read more here.
Keywords: improve prognostic; tumor infiltrating; model; prognostic value ... See more keywords
In vitro 4-1BB stimulation promotes expansion of CD8+ tumor-infiltrating lymphocytes from various sarcoma subtypes
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02568-x
Abstract: Tumor-specific tumor-infiltrating lymphocytes (TILs) can be in vitro expanded and have the ability to induce complete and durable tumor regression in some patients with melanoma following adoptive cell therapy (ACT). In this preclinical study, we… read more here.
Keywords: infiltrating lymphocytes; expansion; stimulation; tumor infiltrating ... See more keywords