Natural MOF‐Like Photocatalytic Nanozymes Alleviate Tumor Pressure for Enhanced Nanodrug Penetration
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DOI: 10.1002/adhm.202400596
Abstract: In oncological nanomedicine, overcoming the dual‐phase high interstitial pressure in the tumor microenvironment is pivotal for enhancing the penetration and efficacy of nanotherapeutics. The elevated tumor interstitial solid pressure (TISP) is largely attributed to the… read more here.
Keywords: pressure; like photocatalytic; mof like; tumor ... See more keywords
Pyroelectric Catalysis-Based "Nano-Lymphatic" Reduces Tumor Interstitial Pressure for Enhanced Penetration and Hydrodynamic Therapy.
Sign Up to like & getrecommendations! Published in 2021 at "ACS nano"
DOI: 10.1021/acsnano.1c03048
Abstract: Because of the deficiency of lymphatic reflux in the tumor, the retention of tumor interstitial fluid causes aggravation of the tumor interstitial pressure (TIP), which leads to unsatisfactory tumor penetration of nanomedicine. It is the… read more here.
Keywords: pyroelectric catalysis; tumor penetration; penetration; tumor interstitial ... See more keywords
Decrease in Tumor Interstitial Pressure for Enhanced Drug Intratumoral Delivery and Synergistic Tumor Therapy.
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DOI: 10.1021/acsnano.2c06356
Abstract: Currently, one of the main reasons for the ineffectiveness of tumor treatment is that the abnormally high tumor interstitial pressure (TIP) hinders the delivery of drugs to the tumor center and promotes intratumoral cell survival… read more here.
Keywords: tumor interstitial; tumor; interstitial pressure; drug ... See more keywords
A New Method for Obtaining Tumor Interstitial Fluid Applied to Cytokine Analysis of Breast Carcinoma Samples
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DOI: 10.21873/anticanres.15600
Abstract: Background/Aim: Tumor interstitial fluid (TIF), a component of the tumor microenvironment, is a valuable source of molecules and substances that help in diagnosis and prognosis of solid tumors. There is still no consensus on the… read more here.
Keywords: tumor interstitial; tumor; method; interstitial fluid ... See more keywords
Application of 3-D Microfluidic Models for Studying Mass Transport Properties of the Tumor Interstitial Matrix
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2019.00006
Abstract: The physical remodeling associated with cancer progression results in barriers to mass transport in the tumor interstitial space. This hindrance ultimately affects the distribution of macromolecules that govern cell fate and potency of cancer therapies.… read more here.
Keywords: matrix; transport; mass transport; application ... See more keywords