Aminocaproylated nanodiamond prodrug for tumor intracellular enhanced delivery of doxorubicin
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.102017
Abstract: Abstract It is urgent to improve the stability of drug system and enhance the curative effect of efficient cancer chemotherapy. In this study, an aminocaproic acid modified nanodiamond-based prodrug (ND-ACA-HYD-DOX NAHD) with pH-activatable fluorescence and… read more here.
Keywords: nanodiamond prodrug; aminocaproylated nanodiamond; delivery; tumor intracellular ... See more keywords
Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Nanoscale"
DOI: 10.1039/d0nr00563k
Abstract: Delivering the pten gene into tumor cells to reacquire PTEN functionality is considered to be an attractive method for cancer treatment. However, the inhibition effect of the tumor intracellular microenvironment (TIME), especially at the high… read more here.
Keywords: system; pten; pten mediated; intracellular microenvironment ... See more keywords