In situ imaging for tumor microbiome interactions via imaging mass cytometry on single‐cell level
Sign Up to like & getrecommendations! Published in 2022 at "Cytometry Part A"
DOI: 10.1002/cyto.a.24550
Abstract: Co‐detection of multiplex cancer subtypes and bacteria subtypes in situ is crucial for understanding tumor microbiome interactions in tumor microenvironment. Current standard techniques such as immunohistochemical staining and immunofluorescence staining are limited for their multiplicity.… read more here.
Keywords: cell; tumor microbiome; breast; situ imaging ... See more keywords
Microbiome harbored within tumors: a new chance to revisit our understanding of cancer pathogenesis and treatment
Sign Up to like & getrecommendations! Published in 2020 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-020-00244-1
Abstract: In a recent study in Science, Nejmen et al. provide the first comprehensive characterization of the tumor microbiome. Their data reveal that the microbiome mostly resides intracellularly in both tumor and immune cells, and that… read more here.
Keywords: tumor microbiome; treatment; within tumors; microbiome ... See more keywords
Predicting pancreatic cancer survival via the tumor microbiome
Sign Up to like & getrecommendations! Published in 2019 at "Nature Medicine"
DOI: 10.1038/s41591-019-0587-z
Abstract: Collagen can be 3D-printed to recreate functional components of the human heart. Direct 3D bioprinting of human cells has the long-term goal to generate tissues and organs appropriate for transplant in cases of organ failure.… read more here.
Keywords: tumor microbiome; cancer survival; via tumor; pancreatic cancer ... See more keywords
Tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer
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DOI: 10.1038/s42003-021-02557-5
Abstract: Despite the uniform mortality in pancreatic adenocarcinoma (PDAC), clinical disease heterogeneity exists with limited genomic differences. A highly aggressive tumor subtype termed ‘basal-like’ was identified to show worse outcomes and higher inflammatory responses. Here, we… read more here.
Keywords: basal like; tumor microbiome; pdac; tumor ... See more keywords
The human tumor microbiome is composed of tumor type–specific intracellular bacteria
Sign Up to like & getrecommendations! Published in 2020 at "Science"
DOI: 10.1126/science.aay9189
Abstract: Profiling tumor bacteria Bacteria are well-known residents in human tumors, but whether their presence is advantageous to the tumors or to the bacteria themselves has been unclear. As an initial step toward addressing this question,… read more here.
Keywords: tumor microbiome; microbiome; tumor type; cancer ... See more keywords
The Role of The Tumor Microbiome in Tumor Development and Its Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.935846
Abstract: Commensal bacteria and other microorganisms that reside in the human body are closely associated with the development and treatment of cancers. Recently, tumor microbiome (TM) has been identified in a variety of cancers such as… read more here.
Keywords: tumor microbiome; role; development treatment; treatment ... See more keywords
Macrophage Phenotype in Combination with Tumor Microbiome Composition Predicts RCC Patients’ Survival: A Pilot Study
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10071516
Abstract: The identification of new prognostic markers of renal cell carcinoma (RCC) is an urgent problem in oncourology. To investigate the potential prognostic significance of tumor microbiome and stromal inflammatory markers, we studied a cohort of… read more here.
Keywords: tumor microbiome; macrophage phenotype; phenotype combination; tumor ... See more keywords