Tumor microtubes connect pancreatic cancer cells in an Arp2/3 complex-dependent manner
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e19-11-0605
Abstract: Actin-based tubular connections between cells have been observed in many cell types. Termed “tunneling nanotubes (TNTs),” “membrane nanotubes,” “tumor microtubes (TMTs),” or “cytonemes,” these protrusions interconnect cells in dynamic networks. Structural features in these protrusions… read more here.
Keywords: cancer cells; cancer; arp2 complex; tumor microtubes ... See more keywords
Tumor microtubes convey resistance to surgical lesions and chemotherapy in gliomas
Sign Up to like & getrecommendations! Published in 2017 at "Neuro-Oncology"
DOI: 10.1093/neuonc/nox070
Abstract: Background Primary and adaptive resistance against chemo- and radiotherapy and local recurrence after surgery limit the benefits from these standard treatments in glioma patients. Recently we found that glioma cells can extend ultra-long membrane protrusions,… read more here.
Keywords: convey resistance; tumor microtubes; resistance; microtubes convey ... See more keywords