Comparison between model‐predicted tumor oxygenation dynamics and vascular‐/flow‐related Doppler indices
Sign Up to like & getrecommendations! Published in 2017 at "Medical Physics"
DOI: 10.1002/mp.12192
Abstract: Purpose Mathematical modeling is a powerful and flexible method to investigate complex phenomena. It discloses the possibility of reproducing expensive as well as invasive experiments in a safe environment with limited costs. This makes it… read more here.
Keywords: tumor oxygenation; doppler; model; flow ... See more keywords
Impact of SBRT fractionation in hypoxia dose painting - Accounting for heterogeneous and dynamic tumor oxygenation.
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DOI: 10.1002/mp.13514
Abstract: PURPOSE Tumor hypoxia, often found in nonsmall cell lung cancer (NSCLC), implies an increased resistance to radiotherapy. Pretreatment assessment of tumor oxygenation is, therefore, warranted in these patients, as functional imaging of hypoxia could be… read more here.
Keywords: tumor oxygenation; heterogeneous dynamic; hypoxia; dose painting ... See more keywords
Eribulin improves tumor oxygenation demonstrated by 18F-DiFA hypoxia imaging, leading to radio-sensitization in human cancer xenograft models
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-021-05544-4
Abstract: Eribulin, an inhibitor of microtubule dynamics, is known to show antitumor effects through its remodeling activity in the tumor vasculature. However, the extent to which the improvement of tumor hypoxia by eribulin affects radio-sensitivity remains… read more here.
Keywords: tumor oxygenation; 18f difa; hypoxia; eribulin ... See more keywords
Tumor Microenvironment-Regulated and Reported Nanoparticles for Overcoming the Self-Confinement of Multiple Photodynamic Therapy.
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DOI: 10.1021/acs.nanolett.0c02272
Abstract: The efficiency of photodynamic therapy (PDT) highly depends on the tumor oxygenation state. However, PDT itself can not only cause oxygen depletion but also prevent oxygen supply in tumors. Such self-confinement effect significantly limits the… read more here.
Keywords: photodynamic therapy; self confinement; tumor oxygenation; tumor microenvironment ... See more keywords
Superparamagnetic Oxygen-Loaded Nanobubbles to Enhance Tumor Oxygenation During Hyperthermia
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.01001
Abstract: Tumor oxygenation is a critical issue for enhancing radiotherapy (RT) effectiveness. Alternating RT with hyperthermia improves tumor radiosensitivity by inducing a massive vasodilation of the neoangiogenic vasculature provided the whole tumor is properly heated. The… read more here.
Keywords: oxygen; oxygen loaded; tumor oxygenation; loaded nanobubbles ... See more keywords
Assessment of Nanoparticle-Mediated Tumor Oxygen Modulation by Photoacoustic Imaging
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DOI: 10.3390/bios12050336
Abstract: Photoacoustic imaging (PAI) is an invaluable tool in biomedical imaging, as it provides anatomical and functional information in real time. Its ability to image at clinically relevant depths with high spatial resolution using endogenous tissues… read more here.
Keywords: photoacoustic imaging; tumor oxygenation; assessment nanoparticle; oxygen ... See more keywords
Overcoming hypoxia-induced chemoresistance to cisplatin through tumor oxygenation monitored by optical imaging
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DOI: 10.7150/ntno.35935
Abstract: Perfluorocarbon nanoparticles have been reported to deliver oxygen to tumors and reduce hypoxia-induced radioresistance, however few studies have been carried out to study its role in reducing hypoxia-induced chemoresistance. The oxygenation effect also varies dramatically… read more here.
Keywords: oxygenation; optical imaging; hypoxia induced; tumor oxygenation ... See more keywords