Tumor purity as a prognosis and immunotherapy relevant feature in gastric cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3505
Abstract: Tumor microenvironment (TME) has been illustrated their clinic pathological significance in predicting outcomes and therapeutic efficacy by more and more studies. Tumor purity, which reflects the features of TME, is defined as the proportion of… read more here.
Keywords: prognosis; tumor purity; gastric cancer; tumor ... See more keywords
Molecular testing of different cytologic preparations in patients with advanced lung adenocarcinoma: which yields the best results?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Society of Cytopathology"
DOI: 10.1016/j.jasc.2016.06.002
Abstract: INTRODUCTION This study constitutes the first systematic comparison of molecular results between different cytology preparations in patients with lung adenocarcinoma undergoing testing for EGFR, KRAS, and BRAF mutations. MATERIALS AND METHODS 115 archival cytology preparations… read more here.
Keywords: lung adenocarcinoma; preparations patients; tumor purity; molecular testing ... See more keywords
TPES: tumor purity estimation from SNVs
Sign Up to like & getrecommendations! Published in 2019 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btz406
Abstract: MOTIVATION Tumor purity (TP) is the proportion of cancer cells in a tumor sample. TP impacts on the accurate assessment of molecular and genomics features as assayed with NGS approaches. State-of-the-art tools mainly rely on… read more here.
Keywords: purity; tumor purity; estimation snvs; purity estimation ... See more keywords
Universal informative CpG sites for inferring tumor purity from DNA methylation microarray data
Sign Up to like & getrecommendations! Published in 2018 at "Journal of bioinformatics and computational biology"
DOI: 10.1142/s0219720017500305
Abstract: Tumor purity is an intrinsic property of tumor samples and potentially has severe impact on many types of data analysis. We have previously developed a statistical method, InfiniumPurify, which could infer purity of a tumor… read more here.
Keywords: methylation; tumor purity; purity; informative cpg ... See more keywords
Abstract 2255: Using tumor sample gene expression data to infer tumor purity levels with stochastic gradient boosting machines
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-2255
Abstract: Tumor purity is the percent of cancer cells present in a sample of tumor tissue. The noncancerous cells (stromal cells) in a tumor are thought to have an important role in tumor growth, metastatic progression,… read more here.
Keywords: purity levels; tumor purity; purity; expression ... See more keywords
RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression
Sign Up to like & getrecommendations! Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-3014-z
Abstract: BackgroundWith the advent of array-based techniques to measure methylation levels in primary tumor samples, systematic investigations of methylomes have widely been performed on a large number of tumor entities. Most of these approaches are not… read more here.
Keywords: array; methylation; tumor purity; purity ... See more keywords
Identification of Signature Genes and Characterizations of Tumor Immune Microenvironment and Tumor Purity in Lung Adenocarcinoma Based on Machine Learning
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.843749
Abstract: The implication of the Estimation of Stromal and Immune cells in Malignant tumor tissues using expression data (ESTIMATE) method to determine the tumor microenvironment (TME) and tumor immune score including tumor purity represents an efficient… read more here.
Keywords: tumor purity; csgtpp; tumor immune; tumor ... See more keywords